{"database":"biostudies-other","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"submitter":["Lucian Smith"],"journal":["Proceedings of the National Academy of Sciences of the United States of America"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/MODEL1904020002"],"repository":["biostudies-other"],"additional_accession":["10.1073/pnas.1816000116"],"pubmed_authors":["Mohammad Umer Sharif Shohan","Lucian Smith","Simon Mitchell"]},"is_claimable":false,"name":"Simon2019 - NIK-dependent p100 processing into p52 and IkBd degradation, Michaelis-Menten, SBML 2v4","description":"

This model represents NIK-dependent p100 processing into p52 and NIK-dependent IkBd degradation with Michaelis-Menten kinetics. Compare this Michaelis-Menten representation to the mass action model in which the dose-response to increasing p100 mRNA is no longer monotonic due to substrate complex competition.

","dates":{"release":"2019-04-02T00:00:00Z","modification":"2025-07-15T09:49:05.205Z","creation":"2025-03-29T21:59:01.143Z"},"accession":"MODEL1904020002","cross_references":{"biomodels___db":["BIOMD0000000869"],"pubmed":["31048505"],"ensembl":["ENSG00000077150"],"ncit":["NCIT:C18888","C97201","C61559"],"mamo":["MAMO_0000046"],"go":["GO:0006397"],"uniprot":["Q00653","Q99558"],"doi":["10.1073/pnas.1816000116"]}}