{"database":"biostudies-other","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["10"],"submitter":["Lucian Smith"],"journal":["Frontiers in immunology"],"pagination":["2401"],"species":["Homo sapiens"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/MODEL1911180002"],"repository":["biostudies-other"],"additional_accession":["31681292"],"pubmed_authors":["Lucian Smith","Johannes Meyer"]},"is_claimable":false,"name":"Coulibaly2019 - Interleukin-15 Signaling in HIF-1a Regulation in Natural Killer Cells","description":"

This is a mathematical model comprised of non-linear ordinary differential equations describing the dynamic relationship between hypoxia-inducible factor-1 alpha (HIF-1a) mRNA, HIF-1a protein, and interleukin-15-mediated upstream signalling events in natural killer cells from human blood. Regulatory expressions are also included for mammalian target of rapamycin (mTOR), nuclear factor-kappa beta, and signal transducer and activator of transcription 3 (STAT3).

","dates":{"release":"2019-11-18T00:00:00Z","modification":"2025-07-15T09:49:08.707Z","creation":"2025-03-29T21:58:48.554Z"},"accession":"MODEL1911180002","cross_references":{"sbo":["SBO:0000177","SBO:0000183","SBO:0000184","SBO:0000393","SBO:0000180","SBO:0000179"],"biomodels___db":["BIOMD0000000867"],"pubmed":["31681292"],"pr":["PR:000003041"],"ncit":["C17380","NCIT:C28553","NCIT:C28664","NCIT:C157205","C19398","C813","NCIT:C64914","C12536","C64382","NCIT:C20214","NCIT:C41625","C20517","NCIT:C64370"],"mod":["MOD:00677"],"mamo":["MAMO_0000046"],"cl":["CL:0000623"],"taxonomy":["9606"]}}