biostudies-otherUnknown10Lucian SmithFrontiers in immunology2401Homo sapienshttps://www.ebi.ac.uk/biostudies/studies/MODEL1911180002biostudies-other31681292Lucian SmithJohannes MeyerfalseCoulibaly2019 - Interleukin-15 Signaling in HIF-1a Regulation in Natural Killer Cells<notes xmlns="http://www.sbml.org/sbml/level2/version4"> <body xmlns="http://www.w3.org/1999/xhtml"> <pre>This is a mathematical model comprised of non-linear ordinary differential equations describing the dynamic relationship between hypoxia-inducible factor-1 alpha (HIF-1a) mRNA, HIF-1a protein, and interleukin-15-mediated upstream signalling events in natural killer cells from human blood. Regulatory expressions are also included for mammalian target of rapamycin (mTOR), nuclear factor-kappa beta, and signal transducer and activator of transcription 3 (STAT3).</pre> </body> </notes>2019-11-18T00:00:00Z2025-07-15T09:49:08.707Z2025-03-29T21:58:48.554ZMODEL1911180002SBO:0000177SBO:0000183SBO:0000184SBO:0000393SBO:0000180SBO:0000179BIOMD000000086731681292PR:000003041C17380NCIT:C28553NCIT:C28664NCIT:C157205C19398C813NCIT:C64914C12536C64382NCIT:C20214NCIT:C41625C20517NCIT:C64370MOD:00677MAMO_0000046CL:00006239606