{"database":"biostudies-other","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["29"],"submitter":["Tung Nguyen"],"journal":["Cell reports"],"pagination":["4553-4567.e7"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/MODEL2009110001"],"repository":["biostudies-other"],"additional_accession":["31875560"],"pubmed_authors":["Tung Nguyen","Lutz Brusch"]},"is_claimable":false,"name":"Kolbe2019 - Spatio-temporal liver zonation","description":"Metabolism of the adult liver in mice and human is spatially zonated with hepatocytes along the axis from each portal vein to the nearest central vein expressing enzymes in a zonated manner. Upstream of that functional zonation, interactions of Wnt and Hh signaling are orchestrating and self-organizing the spatial expression patterns. This spatio-temporal model is derived from experimental data and explores the interacting signaling pathways. To run this model, use the free, open-source software Morpheus (download for Windows, macOS, Linux from https://morpheus.gitlab.io).","dates":{"release":"2020-09-11T00:00:00Z","modification":"2025-07-14T17:05:09.205Z","creation":"2025-03-31T13:22:55.068Z"},"accession":"MODEL2009110001","cross_references":{"pubmed":["31875560"]}}