{"database":"biostudies-other","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["139"],"submitter":["Lucian Smith"],"journal":["Chaos, solitons, and fractals"],"pagination":["110296"],"species":["Severe acute respiratory syndrome coronavirus 2"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/MODEL2012040001"],"repository":["biostudies-other"],"additional_accession":["32982082"],"pubmed_authors":["Lucian Smith","Matthias König","Kausthubh Ramachandran"]},"is_claimable":false,"name":"Malkov2020 - SEIRS model of COVID-19 transmission with reinfection","description":"Epidemiological models of COVID-19 transmission assume that recovered individuals have a fully protected immunity. To date, there is no definite answer about whether people who recover from COVID-19 can be reinfected with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). In the absence of a clear answer about the risk of reinfection, it is instructive to consider the possible scenarios. To study the epidemiological dynamics with the possibility of reinfection, I use a Susceptible-Exposed-Infectious-Resistant-Susceptible model with the time-varying transmission rate. I consider three different ways of modeling reinfection. The crucial feature of this study is that I explore both the difference between the reinfection and no-reinfection scenarios and how the mitigation measures affect this difference. The principal results are the following. First, the dynamics of the reinfection and no-reinfection scenarios are indistinguishable before the infection peak. Second, the mitigation measures delay not only the infection peak, but also the moment when the difference between the reinfection and no-reinfection scenarios becomes prominent. These results are robust to various modeling assumptions.","dates":{"release":"2020-12-04T00:00:00Z","modification":"2025-07-15T09:45:45.286Z","creation":"2025-03-29T22:22:36.888Z"},"accession":"MODEL2012040001","cross_references":{"pubmed":["32982082"],"ncit":["NCIT:C17234","NCIT:C171133","C25746","C25559","NCIT:C16710"],"mamo":["MAMO_0000046"],"ido":["0000514","0000569","0000511","0000597"],"doid":["DOID:0080600"],"taxonomy":["9606","2697049"]}}