biostudies-otherUnknownLouis GallCPT: Pharmacometrics & Systems Pharmacologyhttps://www.ebi.ac.uk/biostudies/studies/MODEL2212120003biostudies-other10.1002/psp4.13029Louis GallfalseGall&Pin2022 - ODE model of the intestinal epitheliumWe developed a compartmental model of the small intestinal epithelium that describes stem and progenitor cell proliferation and differentiation and cell migration onto the villus. The model includes a negative feedback loop from villus cells to regulate crypt proliferation and integrates heterogeneous epithelial-related processes, such as the transcriptional profile, citrulline kinetics and probability of diarrhea.2022-12-12T00:00:00Z2025-07-14T17:32:03.596Z2025-03-30T23:06:44.615ZMODEL221212000310.1002/psp4.13029