biostudies-otherUnknownZainab Ashimiyu-AbdusalamAdvances in Neural Information Processing Systems 33 (NeurIPS 2020)https://www.ebi.ac.uk/biostudies/studies/MODEL2406050003biostudies-other10.48550/arXiv.2007.02835Amna AliZainab Ashimiyu-AbdusalamfalseRong2020 - Grover-Bace: Prediction of Beta-secretase 1 (BACE-1) inhibition.<p>Prediction of Beta-secretase 1 (BACE-1) inhibition. BACE-1 is expressed mainly in neurons and has been involved in the development of Alzheimer's disease. This model has been trained on the BACE dataset from MoleculeNet using the GROVER transformer. </p><p><normal>Model Type:</normal> Predicitive machine learning model.<br><normal>Model Relevance:</normal> Probability that the molecule is a BACE-1 inhibitor.<br><normal>Model Encoded by:</normal> Amna Ali (Ersilia)<br><normal>Metadata Submitted in BioModels by:</normal> Zainab Ashimiyu-Abdusalam</p><p>Implementation of this model code by <a href="https://ersilia.io/">Ersilia</a> is available here: <br><a href="https://github.com/ersilia-os/eos2mhp">https://github.com/ersilia-os/eos2mhp</a></p><img src="https://www.ebi.ac.uk/biomodels/static-assets/images/ersilia-logo.png" alt="Ersilia Logo" width="150">2024-06-05T00:00:00Z2025-07-14T17:01:35.778Z2025-03-31T13:26:39.754ZMODEL2406050003NCIT:C17429C154407CHEBI:3767010.48550/arXiv.2007.02835