{"database":"biostudies-other","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"submitter":[null],"species":["Rattus norvegicus (brown rat)"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-BSST1132"],"repository":["biostudies-other"],"additional_accession":[]},"is_claimable":false,"name":"Conjugation with Tris decreases the risk of ketoprofen-induced mucosal damage - databases","description":"The non-steroid anti-inflammatory drug ketoprofen (Ket) has haemorrhagic side-effects in the upper GI tract. Our aims were thus to develop a new compound from Ket and Tris precursors and compare mucosal effects of Ket and Ket-Tris in a rat model of colitis and in healthy animals. Further, we tested the hypothesis that GI methane generation is associated with the inflammatory activation under these conditions.","dates":{"release":"2023-06-30T00:00:00Z","modification":"2023-06-30T06:45:45.174Z","creation":"2023-06-30T06:45:45.174Z"},"accession":"S-BSST1132","cross_references":{}}