{"database":"biostudies-other","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"submitter":["Jeroen Pennings"],"funding":["Horizon Europe Research and Innovation Programme","European Union’s Horizon 2020 Research and Innovation Programme"],"species":["Homo sapiens (human)"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-BSST2254"],"repository":["biostudies-other"],"funding_grant_id":["101057014","964537"],"pubmed_authors":["Jeroen Pennings"],"additional_accession":[]},"is_claimable":false,"name":"Reactive Oxygen Species formation in HepG2 cells by compound exposure","description":"We quantified ROS formation in HepG2 cells by DCFDA fluorescent probe signal. This was done using five exposure scenarios: (1) HepG2 cells under standard oxygen conditions (20% O2); (2) HepG2 cells under reduced oxygen conditions (3% O2); (3) maturated HepG2 cells receiving acute exposure; (4) maturated HepG2 cells receiving repeated exposure; (5) maturated HepG2 cells receiving repeated exposure and recovery. DCF formation was measured after 1 h of exposure to various compounds at multiple concentrations, as well as several controls.\nThis study was performed as part of the RISK-HUNT3R project and the PARC project.","dates":{"release":"2026-04-30T00:00:00Z","modification":"2026-04-30T01:01:47.592Z","creation":"2025-10-28T08:36:57.479Z"},"accession":"S-BSST2254","cross_references":{}}