{"database":"biostudies-other","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"submitter":["Urs Mörbe"],"funding":["Novo Nordisk Foundation","European Crohn’s and Colitis Organisation ","Lundbeck Foundation","Louis-Hansen-Foundation"],"species":["Homo sapiens (human)"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-BSST2281"],"repository":["biostudies-other"],"funding_grant_id":["R155-2014-4184","NNF22OC0071681"],"pubmed_authors":["Urs Mörbe"],"additional_accession":[]},"is_claimable":false,"name":"Fibroblast diversity within human gut-associated lymphoid tissues","description":"The provided data include the scRNA-seq data and flow cytometry metadata of the study entitled \"Fibroblast diversity within human gut-associated lymphoid tissues\", published in the Journal of Experimental Medicine.\n\nProcedure for scRNA-seq: \nInput: Resection material of patients undergoing surgery for colorectal cancer (healthy controls, samples  taken >10cm from tumour site and macroscopically tumour free) or IBD resections from the distal ileum. Samples were processed to obtain single cell suspensions as described by Jørgensen et al. (PMID: 33619391). Cells were sorted on a BD Aria cell sorter. After sorting, the cells were subjected to single cell RNA-sequencing using the 10x Genomics platform.\n\nscRNA-seq data is provided as read count matrices as well as FASTQ files that were anonymized using the BAMboozled pipeline (PMID: 34711808). FASTQ files: In short, patient identifiable information such as SNPs, insertions and deletions were replaced with the information of the human reference genome to remove person-identifiable information.  \n","dates":{"release":"2025-11-21T00:00:00Z","modification":"2026-04-16T19:52:35.52Z","creation":"2025-11-14T13:27:43.975Z"},"accession":"S-BSST2281","cross_references":{}}