{"database":"biostudies-other","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"submitter":["Furnari Frank"],"species":["Homo sapiens"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-ECPF-GEOD-33442"],"project":["EurocanPlatform"],"abstract":["As a first step towards identifying the target genes of EGFR activity in glioma cells, genome-wide expression analyses were performed using the Affymetrix GeneChip Human Genome U133A array. To accomplish this, mRNA expression levels of these genes were measured in the glioblastoma cell lines, U87 and U178, engineered with EGFR by retrovirus transduction (termed U87-EGFR and U178-EGFR respectively), with or without 20 ng/mL EGF treatment for 3 h. U87 and U178 cells engineered to express EGFR were stimulated with or without  EGF. The experiment was replicated twice for each U87 and U178 cells."],"repository":["biostudies-other"],"experiment_type":["transcription profiling by array"],"data_source":["EurocanPlatform"],"pubmed_authors":["Narita Yoshitaka","Li Ming","Furnari Frank","Mukasa Akitake"],"additional_accession":[]},"is_claimable":false,"name":"The target genes of EGFR activity in glioma cells","description":"As a first step towards identifying the target genes of EGFR activity in glioma cells, genome-wide expression analyses were performed using the Affymetrix GeneChip Human Genome U133A array. To accomplish this, mRNA expression levels of these genes were measured in the glioblastoma cell lines, U87 and U178, engineered with EGFR by retrovirus transduction (termed U87-EGFR and U178-EGFR respectively), with or without 20 ng/mL EGF treatment for 3 h. U87 and U178 cells engineered to express EGFR were stimulated with or without  EGF. The experiment was replicated twice for each U87 and U178 cells.","dates":{"release":"2016-04-14T14:05:00Z","modification":"2016-04-14T14:05:00Z","creation":"2016-04-14T14:05:00Z"},"accession":"S-ECPF-GEOD-33442","cross_references":{"GEO":["GSE33442"],"ArrayExpress":["E-GEOD-33442"],"EFO":["EFO_0005543","EFO_0000322"],"ArrayExpress files":["E-GEOD-33442"]}}