<HashMap><database>biostudies-other</database><scores/><additional><submitter>Creighton CJ</submitter><pagination>R28</pagination><full_dataset_link>https://www.ebi.ac.uk/biostudies/studies/S-ECPF-GEOD-3834</full_dataset_link><project>EurocanPlatform</project><abstract>We generated DNA microarray based gene expression profiles from three estrogen receptor a (ERa) positive breast cancer cell lines stimulated by 17ß-estradiol (E2) in vitro over a time course, as well as from MCF-7 cells grown as xenografts in ovariectomized athymic nude mice with E2 supplementation and after its withdrawal. Experiment Overall Design: 8 MCF-7 xenograft profiles (4 with E2,4 without E2), 14 T47D profiles (with E2 treatment in culture from 0 to 24 hr), 10 BT-474 profiles (with E2 treatment from 0 to 24 hr), 12 MCf-7 profiles (with E2 treatment from 0 to 24 hr)</abstract><repository>biostudies-other</repository><experiment_type>transcription profiling by array</experiment_type><data_source>EurocanPlatform</data_source><omics_type>Unknown</omics_type><volume>7</volume><journal>Genome biology</journal><species>Homo sapiens</species><pubmed_authors>Larios JM</pubmed_authors><pubmed_authors>Miller RS</pubmed_authors><pubmed_authors>Cordero KE</pubmed_authors><pubmed_authors>Johnson MD</pubmed_authors><pubmed_authors>Creighton CJ</pubmed_authors><pubmed_authors>Lippman ME</pubmed_authors><pubmed_authors>Chinnaiyan AM</pubmed_authors><pubmed_authors>Rae JM</pubmed_authors></additional><is_claimable>false</is_claimable><name>Transcription profiling of human ER+ BrC cells with and without estradiol in both cell cultures and xenografts</name><description>We generated DNA microarray based gene expression profiles from three estrogen receptor a (ERa) positive breast cancer cell lines stimulated by 17ß-estradiol (E2) in vitro over a time course, as well as from MCF-7 cells grown as xenografts in ovariectomized athymic nude mice with E2 supplementation and after its withdrawal. Experiment Overall Design: 8 MCF-7 xenograft profiles (4 with E2,4 without E2), 14 T47D profiles (with E2 treatment in culture from 0 to 24 hr), 10 BT-474 profiles (with E2 treatment from 0 to 24 hr), 12 MCf-7 profiles (with E2 treatment from 0 to 24 hr)</description><dates><release>2016-04-14T14:11:49Z</release><publication>2006</publication><modification>2016-04-14T14:11:49Z</modification><creation>2016-04-14T14:11:49Z</creation></dates><accession>S-ECPF-GEOD-3834</accession><cross_references><GEO>GSE3834</GEO><ArrayExpress>E-GEOD-3834</ArrayExpress><EFO>EFO_0000305</EFO><EFO>EFO_0000322</EFO><ArrayExpress files>E-GEOD-3834</ArrayExpress files></cross_references></HashMap>