{"database":"biostudies-other","file_versions":[],"scores":null,"additional":{"submitter":["Sun Y"],"pagination":["20"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-ECPF-GEOD-49644"],"project":["EurocanPlatform"],"abstract":["Epithelial-mesenchymal transition has been implicated in tumor metastasis, cancer drug resistance and cancer stem cell features.  In this study, we examined gene expression profiles of three non-small cell lung cancer cell lines, before and after experimentally induced EMT. We modeled epitheial-mesenchyml transition by culturing A549, HCC827 and NCI-H358 cells in the presence of TGFb for three weeks, and compared gene expression profiles of the paretnal cells and cells after EMT."],"repository":["biostudies-other"],"experiment_type":["transcription profiling by array"],"data_source":["EurocanPlatform"],"omics_type":["Unknown"],"volume":["2"],"journal":["Cancer & metabolism"],"species":["Homo sapiens"],"pubmed_authors":["Hatzivassiliou G","Wilson C","Johnson L","Gao M","Liu P","Zhuang G","Daemen A","Settleman J","Arnott D","Sun Y","Boudreau A"],"additional_accession":[]},"is_claimable":false,"name":"Transcription profiling by array of three non-small cell lung cancer cell lines upon TGFb-induced epithelial-mesenchymal transition (EMT) against untreated counterparts to study EMT's role in tumour metastasis","description":"Epithelial-mesenchymal transition has been implicated in tumor metastasis, cancer drug resistance and cancer stem cell features.  In this study, we examined gene expression profiles of three non-small cell lung cancer cell lines, before and after experimentally induced EMT. We modeled epitheial-mesenchyml transition by culturing A549, HCC827 and NCI-H358 cells in the presence of TGFb for three weeks, and compared gene expression profiles of the paretnal cells and cells after EMT.","dates":{"release":"2016-04-14T14:28:19Z","publication":"2014","modification":"2016-04-14T14:28:19Z","creation":"2016-04-14T14:28:19Z"},"accession":"S-ECPF-GEOD-49644","cross_references":{"GEO":["GSE49644"],"ArrayExpress":["E-GEOD-49644"],"EFO":["EFO_0003060","EFO_0000322"],"ArrayExpress files":["E-GEOD-49644"]}}