<HashMap><database>biostudies-other</database><scores/><additional><submitter>Sun Y</submitter><pagination>20</pagination><full_dataset_link>https://www.ebi.ac.uk/biostudies/studies/S-ECPF-GEOD-49644</full_dataset_link><project>EurocanPlatform</project><abstract>Epithelial-mesenchymal transition has been implicated in tumor metastasis, cancer drug resistance and cancer stem cell features.  In this study, we examined gene expression profiles of three non-small cell lung cancer cell lines, before and after experimentally induced EMT. We modeled epitheial-mesenchyml transition by culturing A549, HCC827 and NCI-H358 cells in the presence of TGFb for three weeks, and compared gene expression profiles of the paretnal cells and cells after EMT.</abstract><repository>biostudies-other</repository><experiment_type>transcription profiling by array</experiment_type><data_source>EurocanPlatform</data_source><omics_type>Unknown</omics_type><volume>2</volume><journal>Cancer &amp; metabolism</journal><species>Homo sapiens</species><pubmed_authors>Hatzivassiliou G</pubmed_authors><pubmed_authors>Wilson C</pubmed_authors><pubmed_authors>Johnson L</pubmed_authors><pubmed_authors>Gao M</pubmed_authors><pubmed_authors>Liu P</pubmed_authors><pubmed_authors>Zhuang G</pubmed_authors><pubmed_authors>Daemen A</pubmed_authors><pubmed_authors>Settleman J</pubmed_authors><pubmed_authors>Arnott D</pubmed_authors><pubmed_authors>Sun Y</pubmed_authors><pubmed_authors>Boudreau A</pubmed_authors></additional><is_claimable>false</is_claimable><name>Transcription profiling by array of three non-small cell lung cancer cell lines upon TGFb-induced epithelial-mesenchymal transition (EMT) against untreated counterparts to study EMT's role in tumour metastasis</name><description>Epithelial-mesenchymal transition has been implicated in tumor metastasis, cancer drug resistance and cancer stem cell features.  In this study, we examined gene expression profiles of three non-small cell lung cancer cell lines, before and after experimentally induced EMT. We modeled epitheial-mesenchyml transition by culturing A549, HCC827 and NCI-H358 cells in the presence of TGFb for three weeks, and compared gene expression profiles of the paretnal cells and cells after EMT.</description><dates><release>2016-04-14T14:28:19Z</release><publication>2014</publication><modification>2016-04-14T14:28:19Z</modification><creation>2016-04-14T14:28:19Z</creation></dates><accession>S-ECPF-GEOD-49644</accession><cross_references><GEO>GSE49644</GEO><ArrayExpress>E-GEOD-49644</ArrayExpress><EFO>EFO_0003060</EFO><EFO>EFO_0000322</EFO><ArrayExpress files>E-GEOD-49644</ArrayExpress files></cross_references></HashMap>