{"database":"biostudies-other","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"submitter":["Holzel Michael"],"species":["Homo sapiens"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-ECPF-GEOD-51221"],"project":["EurocanPlatform"],"abstract":["A panel of 17 human melanoma cell lines with known BRAF and NRAS mutation status was stimulated with TNF-alpha for 72 hours. The goal of the study was to correlate the transcriptional response in BRAF versus NRAS mutated melanoma cell lines. Total RNA was obtained from a panel of 17 human melanoma cell lines treated for 72 hours with TNF-alpha or left untreated. Gene expression profiling was done using the Illumina Human HT12 v4 platform."],"repository":["biostudies-other"],"experiment_type":["transcription profiling by array"],"data_source":["EurocanPlatform"],"pubmed_authors":["Schadendorf Dirk","Tüting Thomas","Landsberg Jennifer","Kohlmeyer Judith","Bald Tobias","Hölzel Michael","Holzel Michael","Rogava Meri","Riesenberg Stefanie"],"additional_accession":[]},"is_claimable":false,"name":"Transcriptional response to TNF-alpha in a panel of 17 human melanoma cell lines","description":"A panel of 17 human melanoma cell lines with known BRAF and NRAS mutation status was stimulated with TNF-alpha for 72 hours. The goal of the study was to correlate the transcriptional response in BRAF versus NRAS mutated melanoma cell lines. Total RNA was obtained from a panel of 17 human melanoma cell lines treated for 72 hours with TNF-alpha or left untreated. Gene expression profiling was done using the Illumina Human HT12 v4 platform.","dates":{"release":"2016-04-14T14:30:25Z","modification":"2016-04-14T14:30:25Z","creation":"2016-04-14T14:30:25Z"},"accession":"S-ECPF-GEOD-51221","cross_references":{"GEO":["GSE51221"],"ArrayExpress":["E-GEOD-51221"],"EFO":["EFO_0000756","EFO_0000322"],"ArrayExpress files":["E-GEOD-51221"]}}