{"database":"biostudies-other","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"submitter":["Fujinaga Takahiro"],"species":["Homo sapiens"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-ECPF-GEOD-54672"],"project":["EurocanPlatform"],"abstract":["Controlling metastatic lesions is an important part of improving cancer prognosis, in addition to controlling the primary lesion. There have been many histological examinations of primary and metastatic lesions, but little basic research using cell strains from primary and metastatic lesions belonging to the same patient. In this study, we successfully established a cell strain derived from lower gingival carcinoma (WK2) and a strain derived from secondary cervical lymph node metastasis (WK3F) through primary cultures of tissue from a patient with oral squamous cell carcinoma. We then investigated the biological characteristics of the cancer cell strains from these primary and metastatic lesions, and analyzed metastasis-related genes.  Comparing the biological characteristics in vitro show"],"repository":["biostudies-other"],"experiment_type":["transcription profiling by array"],"data_source":["EurocanPlatform"],"pubmed_authors":["Wataru Kumamaru","Takahiro Fujinaga","Fujinaga Takahiro"],"additional_accession":[]},"is_claimable":false,"name":"Analysis of biological characterization and metastasis-related genes in cell lines derived from the Primary lesion and lymph node metastasis of a squamous cell carcinoma arising in the mandibular gingiva","description":"Controlling metastatic lesions is an important part of improving cancer prognosis, in addition to controlling the primary lesion. There have been many histological examinations of primary and metastatic lesions, but little basic research using cell strains from primary and metastatic lesions belonging to the same patient. In this study, we successfully established a cell strain derived from lower gingival carcinoma (WK2) and a strain derived from secondary cervical lymph node metastasis (WK3F) through primary cultures of tissue from a patient with oral squamous cell carcinoma. We then investigated the biological characteristics of the cancer cell strains from these primary and metastatic lesions, and analyzed metastasis-related genes.  Comparing the biological characteristics in vitro show","dates":{"release":"2016-04-14T14:34:36Z","modification":"2016-04-14T14:34:36Z","creation":"2016-04-14T14:34:36Z"},"accession":"S-ECPF-GEOD-54672","cross_references":{"GEO":["GSE54672"],"ArrayExpress":["E-GEOD-54672"],"EFO":["EFO_0000199","EFO_0002660"],"ArrayExpress files":["E-GEOD-54672"]}}