biostudies-otherUnknown66(Pt 2)Chen PActa crystallographica. Section E, Structure reports onlineo274https://www.ebi.ac.uk/biostudies/studies/S-EPMC2979877The title compound, C(10)H(7)FO(4), is an inter-mediate in the synthesis of the drug Fidarestat, (2S,4S)-2-aminoformyl-6-fluoro-spiro[chroman-4,4'-imidazolidine]-2',5'-dione. The di-hydro-pyran-one ring adopts an envelope conformation with the asymmetric C atom in the flap position. In the crystal, the mol-ecules are linked into zigzag chains along [100] by O-H?O hydrogen bonds and C-H?? inter-actions involving the benzene ring.biostudies-otherPMC2979877Europe PMCChen PQian SWu YShi ZQfalse6-Fluoro-4-oxochroman-2-carboxylic acid.The title compound, C(10)H(7)FO(4), is an inter-mediate in the synthesis of the drug Fidarestat, (2S,4S)-2-aminoformyl-6-fluoro-spiro[chroman-4,4'-imidazolidine]-2',5'-dione. The di-hydro-pyran-one ring adopts an envelope conformation with the asymmetric C atom in the flap position. In the crystal, the mol-ecules are linked into zigzag chains along [100] by O-H?O hydrogen bonds and C-H?? inter-actions involving the benzene ring.2010-01-01T00:00:00Z2010 2019-03-27T00:00:56Z2019-03-27T00:00:56ZS-EPMC29798772157971110.1107/S1600536809054555