{"database":"biostudies-other","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["7"],"submitter":["Bonnafoux L"],"journal":["Beilstein journal of organic chemistry"],"pagination":["1278-87"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC3182437"],"abstract":["Regioselective bromine-lithium exchange reactions on polybrominated biaryls enable the modular synthesis of various polysubstituted biphenyls such as bis(dialkylphosphino)-, bis(diarylphosphino)- and dialkyl(diaryl)phosphinobiphenyls. All permutations of substituents at the ortho positions of the biphenyls are possible. In a similar manner, one can gain access to monophosphine analogues. So far, such a process, based on the effective discrimination between bromine atoms as a function of their chemical environment, has been observed only sporadically."],"repository":["biostudies-other"],"pmcid":["PMC3182437"],"data_source":["Europe PMC"],"pubmed_authors":["Bonnafoux L","Leroux FR","Colobert F"],"additional_accession":[]},"is_claimable":false,"name":"Bromine-lithium exchange: An efficient tool in the modular construction of biaryl ligands.","description":"Regioselective bromine-lithium exchange reactions on polybrominated biaryls enable the modular synthesis of various polysubstituted biphenyls such as bis(dialkylphosphino)-, bis(diarylphosphino)- and dialkyl(diaryl)phosphinobiphenyls. All permutations of substituents at the ortho positions of the biphenyls are possible. In a similar manner, one can gain access to monophosphine analogues. So far, such a process, based on the effective discrimination between bromine atoms as a function of their chemical environment, has been observed only sporadically.","dates":{"release":"2011-01-01T00:00:00Z","publication":"2011 ","modification":"2019-03-26T22:30:21Z","creation":"2019-03-26T22:30:21Z"},"accession":"S-EPMC3182437","cross_references":{"pubmed":["21977212"],"doi":["10.3762/bjoc.7.148 "]}}