biostudies-otherSmith CRNIGMS NIH HHS1169-71https://www.ebi.ac.uk/biostudies/studies/S-EPMC3384527Indolizine, pyrrolone, and indolizinone heterocycles are easily accessed via the Pt(II)-catalyzed cycloisomerization or a tandem cyclization/1,2-migration of pyridine propargylic alcohols and derivatives. This method provides an efficient synthesis of highly functionalized heterocycles from readily available substrates. [reaction: see text]biostudies-otherEurope PMCUnknown9(6)Organic lettersPMC3384527R01 GM084906Rhodes AJSmith CRBunnelle EMSarpong RfalsePt-catalyzed cyclization/1,2-migration for the synthesis of indolizines, pyrrolones, and indolizinones.Indolizine, pyrrolone, and indolizinone heterocycles are easily accessed via the Pt(II)-catalyzed cycloisomerization or a tandem cyclization/1,2-migration of pyridine propargylic alcohols and derivatives. This method provides an efficient synthesis of highly functionalized heterocycles from readily available substrates. [reaction: see text]2007-01-01T00:00:00Z2007 Mar2019-03-27T00:55:00Z2019-03-27T00:55:00ZS-EPMC33845271730927710.1021/ol0701971