{"database":"biostudies-other","file_versions":[],"scores":null,"additional":{"submitter":["Moeller AH"],"funding":["NIAID NIH HHS","NIGMS NIH HHS"],"pagination":["1179"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC3520023"],"abstract":["Microbes inhabiting the human gastrointestinal tract tend to adopt one of three characteristic community structures, called 'enterotypes', each of which is overrepresented by a distinct set of bacterial genera. Here we report that the gut microbiotae of chimpanzees also assort into enterotypes and that these chimpanzee enterotypes are compositionally analogous to those of humans. Through the analysis of longitudinal samples, we show that the microbial signatures of the enterotypes are stable over time, but that individual hosts switch between enterotypes over periods longer than a year. These results support the hypothesis that enterotypic variation was present in populations of great apes before the divergence of humans and chimpanzees."],"repository":["biostudies-other"],"data_source":["Europe PMC"],"omics_type":["Unknown"],"volume":["3"],"journal":["Nature communications"],"pmcid":["PMC3520023"],"funding_grant_id":["GM101209","T32GM007499","T32 GM007499","R01 AI058715","R01 GM101209"],"pubmed_authors":["Hahn BH","Ochman H","Degnan PH","Pusey AE","Wilson ML","Moeller AH"],"additional_accession":[]},"is_claimable":false,"name":"Chimpanzees and humans harbour compositionally similar gut enterotypes.","description":"Microbes inhabiting the human gastrointestinal tract tend to adopt one of three characteristic community structures, called 'enterotypes', each of which is overrepresented by a distinct set of bacterial genera. Here we report that the gut microbiotae of chimpanzees also assort into enterotypes and that these chimpanzee enterotypes are compositionally analogous to those of humans. Through the analysis of longitudinal samples, we show that the microbial signatures of the enterotypes are stable over time, but that individual hosts switch between enterotypes over periods longer than a year. These results support the hypothesis that enterotypic variation was present in populations of great apes before the divergence of humans and chimpanzees.","dates":{"release":"2012-01-01T00:00:00Z","publication":"2012 ","modification":"2019-03-27T01:01:42Z","creation":"2019-03-27T01:01:42Z"},"accession":"S-EPMC3520023","cross_references":{"pubmed":["23149725"],"doi":["10.1038/ncomms2159 "]}}