{"database":"biostudies-other","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["11(5)"],"submitter":["Liu N"],"journal":["Marine drugs"],"pagination":["1524-33"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC3707159"],"abstract":["Two new oxazole/thiazole derivatives, named tetroazolemycins A (1) and B (2), have been isolated from the acetone extract of the mycelium of Streptomyces olivaceus FXJ8.012 derived from deep-sea water, together with three known compounds, spoxazomicins A-C (3-5), isolated from the fermentation supernatant. The planar structure and relative configuration of tetroazolemycins were elucidated by a combination of spectroscopic analyses, including 1D- and 2D-NMR techniques, and showed to be new pyochelin-type antibiotics. Both compounds showed metal ion-binding activity and their Zn²? complexes exhibited weak activity against pathogenic bacteria Klebsiella pneumoniae."],"repository":["biostudies-other"],"pmcid":["PMC3707159"],"data_source":["Europe PMC"],"pubmed_authors":["Xi L","Huang Y","Liu N","Shang F"],"additional_accession":[]},"is_claimable":false,"name":"Tetroazolemycins A and B, two new oxazole-thiazole siderophores from deep-sea Streptomyces olivaceus FXJ8.012.","description":"Two new oxazole/thiazole derivatives, named tetroazolemycins A (1) and B (2), have been isolated from the acetone extract of the mycelium of Streptomyces olivaceus FXJ8.012 derived from deep-sea water, together with three known compounds, spoxazomicins A-C (3-5), isolated from the fermentation supernatant. The planar structure and relative configuration of tetroazolemycins were elucidated by a combination of spectroscopic analyses, including 1D- and 2D-NMR techniques, and showed to be new pyochelin-type antibiotics. Both compounds showed metal ion-binding activity and their Zn²? complexes exhibited weak activity against pathogenic bacteria Klebsiella pneumoniae.","dates":{"release":"2013-01-01T00:00:00Z","publication":"2013 May","modification":"2019-03-27T01:12:46Z","creation":"2019-03-27T01:12:46Z"},"accession":"S-EPMC3707159","cross_references":{"pubmed":["23665958"],"doi":["10.3390/md11051524 "]}}