biostudies-otherUnknown3(1)Milev MPMolecular & Cellular Oncologye1057314https://www.ebi.ac.uk/biostudies/studies/S-EPMC4845208Mitosis is a highly orchestrated process with morphologically defined stages and is subject to checkpoints that ensure the proper distribution of chromosomes. Centromere-associated protein E (CENP-E), a protein expressed during mitosis, is a potential target of cancer therapeutics. Our laboratory has recently implicated a protein called TRAMM (trafficking of membranes and mitosis) in the recruitment of CENP-E to kinetochores.biostudies-otherEurope PMCMilev MPSacher MfalseTRAMM, a new player in CENP-E biology.Mitosis is a highly orchestrated process with morphologically defined stages and is subject to checkpoints that ensure the proper distribution of chromosomes. Centromere-associated protein E (CENP-E), a protein expressed during mitosis, is a potential target of cancer therapeutics. Our laboratory has recently implicated a protein called TRAMM (trafficking of membranes and mitosis) in the recruitment of CENP-E to kinetochores.2016-01-01T00:00:00Z2016 Jan2019-08-04T08:29:54Z2019-08-04T08:29:54ZS-EPMC484520810.1080/23723556.2015.1057314