dbGaP

application/xml

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Cohortstudy., adult heart, branchial heart, cardium, Herz, Hearts, cardiac structureThe Jackson Heart Study (JHS) is a community-based observational study of cardiovascular disease and its risk factors in African-American adults residing in the three counties, Hinds, Rankin, and Madison, that comprise the Jackson, MS metropolitan area. DNA samples of all JHS participants who provided consent that allows sharing of data through dbGaP, and who had adequate DNA samples available, were included in the TOPMed project.https://www.ncbi.nlm.nih.gov/projects/gap/cgi-bin/study.cgi?study_id=phs000964Manager - Pramod Anugu - Jackson Heart Study, University of Mississippi Medical Center, Jackson, MS USAOther Investigators - Leslie Lange, PhD - Jackson Heart Study, University of Mississippi Medical Center, Jackson, MS USAPrincipal Investigator - Adolfo Correa, MD, MPH, PhD - Jackson Heart Study, University of Mississippi Medical Center, Jackson, MS USAOther Investigators - James Wilson, MD - Jackson Heart Study, University of Mississippi Medical Center, Jackson, MS USAOther Investigators - Solomon Musani, PhD - Jackson Heart Study, University of Mississippi Medical Center, Jackson, MS USAdbGaPOther diseases of pericardium (disorder), Herz, Kinship, degree (angle), Cardiovascular disease, 2410041A17Rik, Laboratory, acetylglucosaminyltransferase-like protein, Other pericardial disease NOS (disorder), FON1, Addresses, Cardiovascular disorder, PAPILLARY MUSCLE DIS NEC, adult heart, Genograms, Genealogical Tree, fs(1)M34, FLORAL ORGAN NUMBER 1, Status, SeS, DmelCG12051, unspecified, Dm-SelD, Disease of cardiovascular system (disorder), Other heart disease NOS, MLASA, HEL-176, CG4601, Life Cycle, 2-amino-3-mercaptopropanoic acid, Research Activity, myd, Laboratory Research, OpT1, DmelCG8553, adult, Priorities, A, Cardiovascular Diseases, C, cyt5C, Sex, Kinship Network, like-acetylglucosaminyltransferase, DHO, D6Pas2, Personnel, M, [X]Other forms of heart disease (disorder), Bdr, Other ill-defined heart disease (disorder), Social Gradients, CG18572, Mbp-1, sideroblastic anaemia and mitochondrial myopathy, cardiac structure, circulatory system disease, Phenotypic, SNAP-25, Social, Disorder of cardiovascular system, sex, Voluntary Worker, sample, Naturalistic Observation Study, DIS, ACT, Act, RG7MT1, l(2)SH1599, close to, Circulatory system disease NOS (disorder), Socioeconomic, Actin/BAP47, CTE-II, AACT, CTE-IIa, Volunteerism, act, Ach1, hBACH, Research Priorities, ACH1, Brother, disease of subdivision of hemolymphoid system, MARIPOSA, act42A, hypotension, Trees, GIG25, Parenthood, count, Su(b), Natural Experiment Study, consent, mKIAA0609, AFFX-Dros-ACTIN_M_r_at, GIG24, Step-Parents, actin, GENA70, Methionin, Hmet, LACH, (2R)-2-amino-3-sulfanylpropanoic acid, susceptibility to multiple system atrophy 1, CARDIOVASC DIS, HGF/SF receptor, Research and Development, fg, Genotypic, 455., oligonucleotide random primer, Multiplication-stimulating polypeptide, DmelCG4027, Parental Age, Disorder of the circulatory system, Parental Ages, RPN5A, [X]Other ill-defined heart diseases (disorder), hCMT1c, c-Met, surveillance, Children, orthostatic, class, Age, AGE, Activities, MDC1D, Middle Class Population, actin5C, enr, ILL-DEFINED HRT DIS NEC, School-Age Population, Telephones, Disease affecting entire cardiovascular system, BACH, Elderly, FLORAL DEFECTIVE 10, l(1)Ab, Act5c, Cardiovascular system disease, 2-amino-4-(methylsulfanyl)butanoic acid, number, L-Zystein, ACT5C, branchial heart, Gm10429, Period Prevalences, SUPERMAN, Other diseases of pericardium, Other disorders of papillary muscle, Adverse, Bach, LARGE1, unspecified (disorder), myopathy with lactic acidosis and sideroblastic anemia, Disorder of cardiovascular system (disorder), Cardiac, Shy-dragger syndrome (formerly), ENSMUSG00000072853, Cell growth-inhibiting gene 24|25 protein, Parenthood Status, Tlr4ap, RCCP2, Other ill-defined heart disease NOS (disorder), Mal, Unspecified circulatory system disorder, Stepparents, Person, School-Age Populations, Brothers, F15E12_6, autonomic failure, Genotypic Sex, 142926_at, Natural Experiment, occurrence, scatter factor receptor, MDDGB6, BRWS2, Volunteer Worker, E-920, prevalence, Socioeconomic Levels, myopathy with lactic acidosis and sideroblastic anaemia, Other forms of heart disease, Hcys, Age Group, Population, Worker, Other specified pericardial disease NOS, ptuf1, Wyatt, fs(1)829, cardiovascular disease, anon-EST:fe2D2, 2-amino-4-(methylthio)butanoic acid, CYSTEINE, DmelCG18572, FREE CYSTEINE, Dm SelD, T11, Development and Research, (2R)-2-amino-3-mercaptopropanoic acid, metionina, Act-5C, Genealogical, SPS1, OTHER SEQUELAE OF MI NEC, Drl, 42A, CPS, Socioeconomic Status, Family Research, EG:EG0002.1, dJ393D12.2, Hearts, Synaptosomal-associated 25 kDa protein, Disease affecting entire cardiovascular system (disorder), deafness, Cell, Mdu, near to, Family Members, N-acetyl-D-glucosamine 2-epimerase, REGULATORY PARTICLE NON-ATPASE SUBUNIT 5A, Public, beta-actin, mda, lactic acidosis and sideroblastic anemia, M32055, family study, Act42, Step-Parent, Other ill-defined heart disease NOS, l(2)k12303, outbreaks, ptf1, ami, Met, MET, ATCMPG1, ATCMPG2, Other specified diseases of pericardium, Cardiovascular, United States of America, Sibling, storage, [X]Other ill-defined heart diseases, PYR1, med, tyrosine-protein kinase Met, [X]Other forms of heart disease, (R)-2-amino-3-mercaptopropanoic acid, Itpr-1, Other sequelae of myocardial infarction, Sister, School Age Populations, 2-Amino-3-mercaptopropionic acid, CVS disease, Genealogic Tree, Genealogic Trees, like-glycosyltransferase, socioeconomic factors, Point, Families, Phenotypic Sex, vicinity of, DRORUD, E920, epidemics, BAP47, ACTSG, sequestering, Relatives, 5730455C01Rik, Bap47, Myopathy, Networks, Ip3r, E 920, Hgfr, Activity, ACTG, Period Prevalence, selection process, ACTE, Other heart disease NOS (disorder), Mbp1, Untrained, 5730555F13Rik, PL93 579, dSPS1, Cardiac Event, Insulin-like growth factor II, [X]Other specified diseases of pericardium (disorder), csp2, Act5, CG11121, l(1)G0420, School-Age, Point Prevalence, old, sampling, dsps1, HGFR, Point Prevalences, SUP, CVD, Cystein, Family Life Cycle, Group, Prevalences, MUB3_18, cisteina, U.S., Untrained Personnel, Public Law 93-579, Other diseases of endocardium, C130027E04Rik, MUB3.18, Social Classes, Super protein, Genogram, SO, sp, retention, Gradient, PL 93-579, act 42A, Ac5C, Switchboard, CG4027, Socioeconomic Level, Services, Familial Study, Research Priority, Family Life Cycles, Event, Volunteer Personnel, Racemethionine, So, Public Law 93 579, Prevalence, proto-oncogene c-Met, l(1)G0330, gyltl1b-b, PRO, Step Parents, frequency, l(2)SH2 1599, 2-Amino-4-(methylthio)butyric acid, OPT, InsP3R, Disorder of circulatory system, LACH1, 9130215G10Rik, Stepparent, CYS, Cys, anon-WO0172774.145, 5730442G03Rik, anon-WO0172774.146, Alpha-1-antichymotrypsin His-Pro-less, MDDGA6, School Age, Voluntary, RENBP, Adverse Cardiac Event, DFNA26, opt, NOS, Other pericardial disease NOS, cardium, KIAA0609, Filiation, Adults, and GLY protein 2, Class, wyatt, GAT, DFNA20, Family Tree, acetylglucosaminyltransferase-like 1A, chromosome 15Q15.3 deletion syndrome, CIRCULATORY DISEASE NOS, IGF-II, HGF receptor, P400, Populations, and GLY protein 1, Parent, gyltl1b, l(1)G0117, Adverse Cardiac Events, mdc1d, JHS, Middle Class, Actin, LARGE_HUMAN, morbidity, beta-actin/Bap47, L-Cystein, Genealogical Trees, l(1)G0486, l(1)G0245, Life Cycles, Genetic Identity, l(1)G0009, CG8553, ZIP code, ACTL3, Lach1, Sisters, Switchboard Services, Cardiovascular Disorders, ASCVD, l(1)G0010, Family Member, Family Trees, MyD88-2, Other heart disease (disorder), Privacy, Preptin, CG12051, Network, Serpin A3, presence, Identity, froggy, Gyltl1a, selD, and Male infertility, MYH9.11, l(1)G0025, IP3R1, Volunteer Workers, [X]Cardiovascular disease, HGF, Switchboard Service, DmelCG11121, Pcp1, MYH9_11, F15E12.6, Level, Caste, Pure, Yin, sensorineural deafness and male infertility, study, Other diseases of endocardium (disorder), act5C, somda, [X]Other specified diseases of pericardium, Genetic, Research, PL 93 579, Other heart disease, Law 93-579, LARGE, Privacy Act, CG2913, Msa, MSA, cleft LIP/palate with abnormal thumbs and microcephaly, AUTS9, BPFD#36, Act42a, Mif1, RANDOM, 1700027G07Rik, Ages, Voluntary Workers, Disease of cardiovascular system, Kinship Networks, AI838057, School Age Population, African unspecified, Family, Circulatory system disease NOS, Cte-II, incidence, BACTS1, sensorineural, PL93-579, l(1)G0177, Disease, Other ill-defined heart diseases, DL-Methionine, selD/sps1, RnBP, not elsewhere classified, Parental, GlcNAc 2-epimerase, Tree, Identities, Other ill-defined heart disease, ptuf, count in organism, Cardiac Events, Priority, CAD, Period, Castes, Research Activities, Genealogic, ACTA3, Pcp-1, Other forms of heart disease (disorder), Social Gradient, PERICARDIAL DISEASE NEC, sideroblastic anemia and mitochondrial myopathy, Zystein, Random selection by shearing, l(1)G0079, Volunteer, 2-amino-3-sulfanylpropanoic acid, VSCM, act 5C, L-2-Amino-3-mercaptopropionic acid, FLO10, America, arc degree, HERP, OPT1, Genetic Identities, endemics, sample population, Cardiovascular Disease, EMBRYO DEFECTIVE 2107, requirements, Other specified pericardial disease NOS (disorder), sample collection, Service, opt1, approaches, DmelCG2913, Indexes, SNAP, AA407980, cardinality, alpha-amino-gamma-methylmercaptobutyric acid, renin-binding protein, Middle Class Populations, Major Adverse Cardiac Events, Par4, Multiplication-stimulating activity, Actin5C, glycosyltransferase-like protein LARGE1, SF receptorfalseNHLBI TOPMed: The Jackson Heart StudySince there is a greater prevalence of cardiovascular disease among African Americans, the purpose of the Jackson Heart Study (JHS) is to explore the reasons for this disparity and to uncover new approaches to reduce it. The JHS is a large, community-based, observational study whose 5306 participants were recruited from among the non-institutionalized African-American adults from urban and rural areas of the three counties (Hinds, Madison, and Rankin) that make up the Jackson, MS, metropolitan statistical area (MSA). Jackson is the capital of Mississippi, the state with the largest percentage (36.3%) of African Americans in the United States. The JHS design included participants from the Jackson ARIC study who had originally been recruited through random selection from a drivers' license registry. Approximately six months before the JHS was to begin, an amendment to the federal Driver's Privacy Protection Act was passed that changed the level of consent for public release of personal information from driver's license lists from an "opt out" to an "opt in" basis. The Mississippi Highway Patrol was no longer able to release a complete listing of all persons with driver's licenses or state identification cards, which prevented its use in the JHS. New JHS participants were chosen randomly from the Accudata America commercial listing, which provides householder name, address, zip code, phone number (if available), age group in decades, and family components. The Accudata list was deemed to provide the most complete count of households for individuals aged 55 years and older in the Jackson MSA. A structured volunteer sample was also included in which demographic cells for recruitment were designed to mirror the eligible population. Enrollment was opened to volunteers who met census-derived age, sex, and socioeconomic status (SES) eligibility criteria for the Jackson MSA. In addition, a family component was included in the JHS. The sampling frame for the family study was a participant in any one of the ARlC, random, or volunteer samples whose family size met eligibility requirements. Eligibility included having at least two full siblings and four first degree relatives (parents, siblings, children over the age of 21) who lived in the Jackson MSA and who were willing to participate in the study. No upper age limit was placed on the family sample. Known contact information was obtained during the baseline clinic examination from the index family member with a verbal pedigree format to identify name(s), age(s), address (es), and telephone number(s). Recruitment was limited to persons 35-84 years old except in the family cohort, where those 21 years old and above were eligible. Only persons who otherwise met study criteria but were deemed to be physically or mentally incompetent by trained recruiters were excluded from study eligibility.1 1 Wyatt SB, Diekelmann N, Henderson F, Andrew ME, Billingsley G, Felder SH et al. A community-driven model of research participation: the Jackson Heart Study Participant Recruitment and Retention Study. Ethn Dis 2003; 13(4):438-455.2018-09-142018-01-09phs000964Diabetes Mellitus18805107257450612128367025393378245751232433215019180233244623701980849925065297163179831817988725561047229589012548714925411155254774292243888419148283252244542315683423156838231568392506506921325150205709162437929725575548257799702218625525920552