{"database":"ecrin-mdr-crc","file_versions":[],"scores":null,"additional":{"omics_type":["Clinical"],"study_start_year":["2023"],"data_sharing_plan":["IPD Sharing (as of February 2023): No"],"condition":["Carcinoma","Advanced Ovarian Carcinoma","Metastatic Ovarian Carcinoma","Metastatic Colorectal Carcinoma","Colorectal cancer","Advanced Colorectal Carcinoma","Metastatic Renal Cell Carcinoma","Ovarian cancer","Advanced Renal Cell Carcinoma","Advanced Pancreatic Carcinoma","Metastatic Pancreatic Carcinoma","Pancreatic cancer","Carcinoma, Ovarian Epithelial","Colorectal Neoplasms","Carcinoma, Renal Cell","Solid tumors","Ovarian Neoplasms","Pancreatic Neoplasms"],"disease":["Carcinoma","Advanced Ovarian Carcinoma","Metastatic Ovarian Carcinoma","Metastatic Colorectal Carcinoma","Advanced Colorectal Carcinoma","Colorectal Cancer","Pancreatic Cancer","Metastatic Renal Cell Carcinoma","Advanced Renal Cell Carcinoma","Ovarian Cancer","Advanced Pancreatic Carcinoma","Metastatic Pancreatic Carcinoma","Carcinoma, Ovarian Epithelial","Carcinoma, Renal Cell","Colorectal Neoplasms","Ovarian Neoplasms","Pancreatic Neoplasms","Solid Tumors"],"study_type":["Interventional"],"full_dataset_link":["https://newmdr.ecrin.org/Study/10788"],"location":["Poland"],"study_start_month":["1"],"keyword":["Renal cancer"],"repository":["ECRIN MDR"],"study_status":["Recruiting"],"additional_accession":[]},"is_claimable":false,"name":"First-in-human Phase I Study to Evaluate Safety, Tolerability and Antineoplastic Activity of OATD-02 in Patients With Selected Advanced and/or Metastatic Solid Tumours","description":"The goal of this clinical trial is to learn if the OATD-02 administration (orally) in monotherapy is safe and has the pharmacodynamic potential to restore and enhance tumour responses to immunotherapy through increased arginine levels or intrinsic anti-tumour activity in participants with advanced metastatic colorectal cancer, ovarian cancer, renal cancer or pancreatic cancer.","dates":{"creation":"2023-01-15"},"accession":"10788","cross_references":{"ClinicalTrials___gov":["NCT05759923"]}}