ecrin-mdr-crcClinical2023Rectal NeoplasmsColorectal cancerLocally Advanced Rectal CancerRectal NeoplasmsColorectal CancerLocally Advanced Rectal CancerInterventionalhttps://newmdr.ecrin.org/Study/134674TME surgeryOxaliplatinCapecitabinePelvic short-course radiotherapyAK104PCRECRIN MDRNot yet recruitingfalseAssess the Efficacy of Radiotherapy and Sequential Chemotherapy and AK104 Before TME Surgery for Local CRC（AK104-IIT-13）This study is a single-arm, open-label, multicenter clinical study to evaluate the efficacy and safety of preoperative short-course radiotherapy combined with AK104 and chemotherapy + TME surgery in patients with advanced rectal cancer.2023-04-1513467NCT05794750