{"database":"ecrin-mdr-crc","file_versions":[],"scores":null,"additional":{"omics_type":["Clinical"],"study_start_year":["2001"],"condition":["Sarcoma","Cervical Cancer","Head and Neck Cancer","Colorectal Cancer","Liver Metastasis","Rectal Cancer","Breast Cancer","Pelvic Cancer","Head and Neck Neoplasms","Mouth Neoplasms","Ovarian Cancer","Mouth Cancer","Neoplasm Metastasis","Colorectal Neoplasms","Pelvic Neoplasms"],"disease":["Sarcoma","Cervical Cancer","Colorectal Cancer","Liver Metastasis","Head And Neck Neoplasms","Rectal Cancer","Breast Cancer","Pelvic Cancer","Mouth Neoplasms","Ovarian Cancer","Mouth Cancer","Neoplasm Metastasis","Colorectal Neoplasms","Head And Neck Cancer","Pelvic Neoplasms"],"study_type":["Interventional"],"full_dataset_link":["https://newmdr.ecrin.org/Study/2007002"],"location":["United States"],"study_start_month":["11"],"keyword":["Bulky Tumor","Lymphadenopathy","Talaporfin","Oral Cancer","Anal Cancer","Photodynamic Therapy","Recurrent","Pelvic Tumors","Refractory Tumor"],"repository":["ECRIN MDR"],"study_status":["Completed"],"additional_accession":[]},"is_claimable":false,"name":"Photodynamic Therapy System for Patients With Refractory/Unresponsive Solid Tumors","description":"This multi-center photodynamic therapy study plans to treat patients with large tumors in any superficial location, sarcoma, tumors of oral/oro-pharyngeal cavity, tumors with extensive pelvic involvement, or liver metastasis. The treatment is limited to patients that have failed to respond to currently approved methods of treatment. The study involves a single, intravenous administration of an investigational drug, LS11 (previously studied in approximately 80 cancer patients) and the placement of a novel, flexible light delivery catheter inside the tumor by a minor surgical procedure. The activation of LS11 by the light delivery catheter over a period of 1-24 hrs may result in destruction of tumor tissue.","dates":{"creation":"2001-11-15"},"accession":"2007002","cross_references":{"ClinicalTrials___gov":["NCT00028405"]}}