ecrin-mdr-crcClinical2001SarcomaCervical CancerHead and Neck CancerColorectal CancerLiver MetastasisRectal CancerBreast CancerPelvic CancerHead and Neck NeoplasmsMouth NeoplasmsOvarian CancerMouth CancerNeoplasm MetastasisColorectal NeoplasmsPelvic NeoplasmsSarcomaCervical CancerColorectal CancerLiver MetastasisHead And Neck NeoplasmsRectal CancerBreast CancerPelvic CancerMouth NeoplasmsOvarian CancerMouth CancerNeoplasm MetastasisColorectal NeoplasmsHead And Neck CancerPelvic NeoplasmsInterventionalhttps://newmdr.ecrin.org/Study/2007002United States11Bulky TumorLymphadenopathyTalaporfinOral CancerAnal CancerPhotodynamic TherapyRecurrentPelvic TumorsRefractory TumorECRIN MDRCompletedfalsePhotodynamic Therapy System for Patients With Refractory/Unresponsive Solid TumorsThis multi-center photodynamic therapy study plans to treat patients with large tumors in any superficial location, sarcoma, tumors of oral/oro-pharyngeal cavity, tumors with extensive pelvic involvement, or liver metastasis. The treatment is limited to patients that have failed to respond to currently approved methods of treatment. The study involves a single, intravenous administration of an investigational drug, LS11 (previously studied in approximately 80 cancer patients) and the placement of a novel, flexible light delivery catheter inside the tumor by a minor surgical procedure. The activation of LS11 by the light delivery catheter over a period of 1-24 hrs may result in destruction of tumor tissue.2001-11-152007002NCT00028405