ecrin-mdr-crcClinical2000Colorectal CancerColorectal NeoplasmsColorectal CancerColorectal NeoplasmsInterventionalhttps://newmdr.ecrin.org/Study/2020221Japan4IrinotecanLeucovorinIrinotecan, leucovorin, fluorouracil, PhaseI/II, colorectal cancer,FluorouracilECRIN MDRCompletedfalsePhase I / II Study of Irinotecan (CPT-11) Combined With l-Leucovorin (l-LV) and 5-FU in Patients With Advanced Colorectal CancerWe performed a phase I/II study of CPT-11/5FU/l-LV in advanced colorectal cancer, to determine the optimal dose of CPT-11 and to estimate the safety and efficacy of this regimen2000-04-152020221NCT00209625