ecrin-mdr-crcClinical2007IPD Sharing (as of May 2017): Yes Description: http://www.merck.com/clinical-trials/pdf/Merck%20Procedure%20on%20Clinical%20Trial%20Data%20Access%20Final_Updated%20July_9_2014.pdf http://engagezone.msd.com/ds_documentation.phpAdvanced Aerodigestive Tract Cancers (Colorectal Cancer (CRC), Non Small Cell Lung Cancer (NSCLC), Head and Neck (H&N), Esophageal CancerColorectal NeoplasmCarcinoma, Non-Small-Cell LungEsophageal NeoplasmHead and Neck Neoplasm9 Colon, unspecified-C349 Bronchus or lung, unspecified-C760 Head, face and neck-C159 Oesophagus, unspecifiedNeoplasmsHead and Neck NeoplasmsHead, face and neckNeoplasmOesophagus, unspecifiedEsophageal NeoplasmsColorectal NeoplasmsBronchus or lung, unspecifiedColon, unspecifiedColon, UnspecifiedAdvanced Aerodigestive Tract Cancers (colorectal Cancer (crc), Non Small Cell Lung Cancer (nsclc), Head And Neck (h&n), Esophageal CancerColorectal NeoplasmHead And Neck NeoplasmEsophageal NeoplasmHead And Neck NeoplasmsNeoplasmsNeoplasmBronchus Or Lung, UnspecifiedHead, Face And NeckEsophageal NeoplasmsColorectal NeoplasmsCarcinoma, Non-small-cell Lung9 Colon, Unspecified-c349 Bronchus Or Lung, Unspecified-c760 Head, Face And Neck-c159 Oesophagus, UnspecifiedOesophagus, UnspecifiedInterventionalhttps://newmdr.ecrin.org/Study/2036207Puerto RicoCzechiaUnited StatesUnited KingdomPortugalSwitzerlandSpainGreeceCanadaNetherlandsSwedenBrazilMexicoItalyAustralia1TemozolomideECRIN MDRTerminatedfalsePhase 2 Study of Temozolomide in Pre-Selected Advanced Aerodigestive Tract Cancers (Study P04273AM2)(TERMINATED)This study is proposed to evaluate the efficacy and safety of temozolomide, an oral anti-cancer agent, in a participant population selected for a biomarker. Participants with colorectal cancer, non-small-cell lung cancer, head and neck cancer, or esophageal cancer will be included.2007-01-152036207NCT004231502006-003169-15PER-023-07