ecrin-mdr-crcClinical2010PainConstipationModerate to severe chronic non-cancer or cancer pain with opioid induced constipationModerate To Severe Chronic Non-cancer Or Cancer Pain With Opioid Induced ConstipationPainConstipationInterventionalhttps://newmdr.ecrin.org/Study/2079187RomaniaCzechiaUnited StatesUnited KingdomSwitzerlandAustriaNetherlandsBelgiumFinlandDenmarkPolandIsraelFranceAustraliaGermany18 mg Naloxone Hydrochloride Prolonged Release TabletsHydromorphoneNaloxone2 mg Naloxone Hydrochloride Prolonged Release TabletsPalladone SR capsulesConfirmatory32 mg Naloxone Hydrochloride Prolonged Release TabletsECRIN MDRCompletedfalseOptimisation of Hydromorphone - Naloxone Ratio for the Treatment of PainThe purpose of this study is to establish an optimal hydromorphone - naloxone ratio with an improved bowel function for constipated pain patients.2010-01-152079187NCT009925762008-005315-182008-005312-18