ecrin-mdr-crcClinical2009Rectal NeoplasmsCancer-Bowel-Back passage (rectum) or large bowel (colon)Rectal CancerLocally Advanced Rectal CancerRectal NeoplasmsCancer-bowel-back Passage (rectum) Or Large Bowel (colon)Rectal CancerLocally Advanced Rectal CancerInterventionalhttps://newmdr.ecrin.org/Study/2080802Australia11ChemotherapyOxaliplatinLeucovorinRadiotherapyFluorouracilECRIN MDRCompletedfalsePreoperative Radiotherapy and Chemotherapy in Patients With Locally Advanced Rectal CancerThe aims of the trial are (1) to determine the tolerability rate in the setting of a multi-centre study and (2) to determine secondary tolerability endpoints, toxicity rates and complete pathologic response rate in patients with locally advanced rectal cancer who are treated with an integrated preoperative radiotherapy with FOLFOX chemotherapy regimen.2009-11-152080802NCT01013805ACTRN12610000175077