ecrin-mdr-crcClinical2010IPD Sharing (as of April 2021): NoAdenocarcinomaPancreatic Adenocarcinoma Non-resectablePancreatic Adenocarcinoma MetastaticColorectal Cancer MetastaticColorectal NeoplasmsAdenocarcinomaPancreatic Adenocarcinoma Non-resectablePancreatic Adenocarcinoma MetastaticColorectal Cancer MetastaticColorectal NeoplasmsInterventionalhttps://newmdr.ecrin.org/Study/2083735United States4MacrobeadMouse cellsBiologicalECRIN MDRCompletedfalseOpen-Label Phase 2 Efficacy Trial of Cancer Macrobeads in Patients With Treatment-Resistant Pancreatic/Colorectal CancerThis is a clinical research study of an investigational (FDA BB-IND 10091) treatment for patients with pancreatic cancer (all stages) and advanced colorectal cancer that no longer responds to standard therapies. The treatment is being evaluated for its effect on tumor growth. It consists of the placement (implantation) of small beads that contain mouse renal adenocarcinoma cells (RENCA macrobeads). The cells in the macrobeads produce substances that have been shown to slow or stop the growth of tumors in experimental animals and veterinary patients. It has been tested in 31 human subjects with different types of cancers in a Phase I safety trial. Phase II studies in patients with colorectal, pancreatic or prostate cancers are in progress.2010-04-152083735NCT01053013