{"database":"ecrin-mdr-crc","file_versions":[],"scores":null,"additional":{"omics_type":["Clinical"],"study_start_year":["2020"],"data_sharing_plan":["IPD Sharing (as of October 2023): No"],"condition":["Prophylactic surgery","pazienti affetti da tumore del colon-retto (CRC) ad alto rischio di sviluppare carcinosi peritoneale","Colorectal cancer","Colon neoplasm","Colorectal Neoplasms","patients with colorectal carcinoma at high risk peritoneal carcinomatosis"],"disease":["Pazienti Affetti Da Tumore Del Colon-retto (crc) Ad Alto Rischio Di Sviluppare Carcinosi Peritoneale","Colon Neoplasm","Colorectal Cancer","Colorectal Neoplasms","Patients With Colorectal Carcinoma At High Risk Peritoneal Carcinomatosis","Prophylactic Surgery"],"study_type":["Interventional"],"full_dataset_link":["https://newmdr.ecrin.org/Study/2302856"],"location":["Italy"],"study_start_month":["6"],"keyword":["Mitomycins","Mitomycin","HIPEC CO2"],"repository":["ECRIN MDR"],"study_status":["Recruiting"],"additional_accession":[]},"is_claimable":false,"name":"Prophylactic Surgery Plus HIPEC With CO2 in Patients Affected by Colorectal Carcinoma. CHECK Study.","description":"This is a phase III randomized, multicenter study with two different arm:\n* experimental: prophylactic surgery plus HIPEC CO2 performed with mitomycin\n* comparator: standard surgery Adjuvant treatment after surgery is mandatory except for documented cases of non-eligibility.\nPatient will be randomized in a 1:1 ratio. Randomization will be done during surgery if the total resection of tumour will be reached and will use a stratification procedure based on center","dates":{"creation":"2020-06-15"},"accession":"2302856","cross_references":{"ClinicalTrials___gov":["NCT03914820"],"EU Clinical Trials Register":["2019-001437-14"]}}