{"database":"ecrin-mdr-crc","file_versions":[],"scores":null,"additional":{"omics_type":["Clinical"],"study_start_year":["2020"],"condition":["Colorectal cancer"],"disease":["Colorectal Cancer"],"study_type":["Observational"],"full_dataset_link":["https://newmdr.ecrin.org/Study/2442405"],"location":["Netherlands"],"study_start_month":["7"],"repository":["ECRIN MDR"],"study_status":["Recruiting"],"additional_accession":[]},"is_claimable":false,"name":"Role Of Ovarian Metastases In Colorectal Cancer (ROMIC): a Dutch study protocol to evaluate the effect of prophylactic salpingo-oophorectomy in postmenopausal women","description":"Interventions: This study evaluates the effect of an existing procedure implemented in the local CRC pathway as follows: prophylactic salpingo-oophorectomy versus standard care in a female population with colorectal cancer.\nPrimary outcome(s): The main aim of this study is to determine whether prophylactic bilateral salpingo-oophorectomy conducted in postmenopausal patients aged =60 years during surgery for primary CRC reduces the incidence of ovarian malignancies (metastatic or primary) during a three-year follow-up period. Moreover, this study will provide the data necessary to calculate the number needed to treat (NNT) in order to prevent one case of ovarian cancer (metastatic or primary).\nStudy Design: Non-randomized controlled trial, Open (masking not used), Active, Parallel","dates":{"creation":"2020-07-15"},"accession":"2442405","cross_references":{"Netherlands National Trial Register":["NL7870"]}}