ecrin-mdr-crcClinical2012Metastases to liverMetastatisk tarmkræft der udgår fra tyk- eller endetarmMetastatic colon or rectal cancerColorectal cancer stage IVColorectal Cancer Stage IvMetastatisk Tarmkræft Der Udgår Fra Tyk- Eller EndetarmMetastases To LiverMetastatic Colon Or Rectal CancerInterventionalhttps://newmdr.ecrin.org/Study/2530271Denmark4XelodairinotecanoxaliplatinAvastinECRIN MDROngoingfalseIndividualised choise of 1.line chemotherapy of metastatic colo-rectal cancer. Can the blood test: TIMP-1 help the doctor to choose the best chemotherapy for the individual patient?Primary objectives: Aim is to investigate whether or not the cancer marker plasma TIMP-1 is related to probability of treatment response on chemotherapy with or without irinotecan Primary endpoints: Progression free survival (PFS)2012-04-1525302712011-005495-42