ecrin-mdr-crcClinical2020Colorectal cancer metastaticColorectal cancer stage IVColorectal Cancer Stage IvColorectal Cancer MetastaticInterventionalhttps://newmdr.ecrin.org/Study/2540754Denmark12IrinotecanOxaliplatinCalciumfolinateCapecitabinFluorouracilECRIN MDROngoingfalseOPTIMISE: A study investigating if analysis of cancer DNA in blood can be used to guide adjuvant treatment in patients with advanced colorectal cancerPrimary objectives: The primary aim of the present study is thus to investigate – in a randomized trial – the clinical utility of circulating tumor DNA analysis to guide treatment decisions in oligometastatic colorectal cancer. Primary endpoints: Rate of patients free from recurrent CRC at 2 years post local treatment2020-12-1525407542020-004524-41