{"database":"ecrin-mdr-crc","file_versions":[],"scores":null,"additional":{"omics_type":["Clinical"],"study_start_year":["2022"],"condition":["Colorectal cancer","Cancer-Biliary tree (gall bladder and bile duct)","Cancer-Bowel-Anal","Cancer-Liver","Cancer-Pancreatic","Hepatobiliary cancer","Cancer-Bowel-Small bowel (duodenum and ileum)","Cancer-Oesophageal (gullet)","Oesophageal cancer","Pancreatic cancer","Cancer-Bowel-Back passage (rectum) or large bowel (colon)","Cancer recurrence","Gastric cancer","Cancer-Stomach"],"disease":["Cancer-bowel-anal","Cancer-bowel-small Bowel (duodenum And Ileum)","Colorectal Cancer","Hepatobiliary Cancer","Cancer-oesophageal (gullet)","Pancreatic Cancer","Cancer Recurrence","Cancer-liver","Cancer-biliary Tree (gall Bladder And Bile Duct)","Cancer-pancreatic","Oesophageal Cancer","Cancer-stomach","Gastric Cancer","Cancer-bowel-back Passage (rectum) Or Large Bowel (colon)"],"study_type":["Observational"],"full_dataset_link":["https://newmdr.ecrin.org/Study/2754854"],"location":["Australia"],"study_start_month":["8"],"repository":["ECRIN MDR"],"study_status":["Not yet recruiting"],"additional_accession":[]},"is_claimable":false,"name":"Tranexamic Acid and Cancer Recurrence after Gastrointestinal Cancer Surgery; A nested substudy of the Tranexamic Acid to Reduce Infection After Gastrointestinal Cancer Surgery (TRIGS) trial","description":"Interventions: This substudy nested within the multicentre, pragmatic, double-blind, randomised TRIGS trial NCT04192435. Assessment will be completed once at 5 years post operatively via cancer registry and the National Death Index (NDI will compare cancer-free survival in patients receiving tranexamic acid, or matched p)lacebo, for gastrointestinal cancer surgery. All adult patients scheduled for elective or semi-elective open or lap-assisted gastrointestinal cancer surgery (oesophageal, gastric, hepatobiliary, pancreatic, colorectal) with one or more risk factors for complications, will be included.\nPrimary outcome(s): Cancer-free survival form state cancer registries[5 years from Gastrointestinal surgery]\nStudy Design: Purpose: Natural history;Duration: Longitudinal;Selection: Defined population;Timing: Prospective","dates":{"creation":"2022-08-15"},"accession":"2754854","cross_references":{"Australian New Zealand Clinical Trials Registry":["ACTRN12622000995774"]}}