{"database":"EGA","file_versions":[],"scores":null,"additional":{"omics_type":["Genomics"],"dataset_type":["Illumina HiSeq 2500;"],"full_dataset_link":["https://ega-archive.org/datasets/EGAD00001000726"],"sample_count":["30"],"description":["EGA dataset EGAD00001000726"],"repository":["EGA"],"title":["Whole transcriptome sequencing of Acute Myeloid Leukemias with an acquired inv(3)(q21q26) or t(3;3)(q21;q26) aberration"],"name_synonyms":["Vasp, hemophilia, hemophilia A, DmelCG15112, ENHANCER OF ATNSI ACTIVITY, classical hemophilia, classic hemophilia, factor 8 deficiency, Data Set, autosomal haemophilia a, 2-hydroxyethyl methacrylate, NDPP1, F8C, F8B, AHF., Haemophilia A, haemophilia A, l(2)02029, enb, hem A, FVIII, VASP, classic haemophilia, DXS1253E, congenital, Historesin, 2-propenoic acid, MENA, HEMA, classic, 2-methyl-, Enb, ENA, Ena, autosomal hemophilia a, CG15112, 2-hydroxyethyl ester, glycol methacrylate, classical haemophilia, ENA/VASP"],"description_synonyms":["Myelogenous Leukemias, Myelocytic, Mds1-Evi1, Acute Myeloblastic, PRDM3, NPH2, Nonlymphocytic Leukemia, Myeloid, Myelocytic Leukemia, Jbo, RNA-seq., Acute Myeloid, Acute Myelocytic Leukemias, in, IV, xEvi-1, Acute Nonlymphoblastic, Acute Myelocytic, chemokine receptor CCR7, MDS1, Mds1, Whole Transcriptome Shotgun Sequencing, Myeloblastic Leukemia, C-C CKR-7, EBI1, Leukemia, GP63, Acute Myelogenous, Acute Myeloblastic Leukemia, CDw197, AW455512, Myelogenous Leukemia, Acute Nonlymphocytic Leukemias, NPHP2, Evi1, EVI1, Ebi1h, D630039M04Rik, Evi-1, Acute Myeloid Leukemia without Maturation, Acute Nonlymphoblastic Leukemia, Acute Nonlymphocytic Leukemia, AI428552, MSP, Myeloid Leukemia, Myelocytic Leukemias, epstein-Barr virus-induced G-protein coupled receptor 1, ANLL, MDS1-EVI1, Nonlymphoblastic Leukemias, evi1, Nphp2, Myelogenous, Engrailed/Invected, M1, M2, CMKBR7, RNA-seq, CCR7, not genetically inherited, Leukemias, Mds, Acute Myelocytic Leukemia, Nonlymphoblastic Leukemia, whole transcriptome, Nonlymphocytic Leukemias, Nonlymphoblastic, Acute Myeloid Leukemias, CC-CKR-7, er, Myeloid Leukemias, IX14, MIP-3 beta receptor, Acute Nonlymphocytic, evi-1, Acute Myelogenous Leukemia, CD197, AML1-EVI-1, mecom, evi1-B, Myeloblastic, INV, Inv, Myeloblastic Leukemias, Acute Myeloid Leukemia, CCR-7, Nonlymphocytic, Acute Myeloid Leukemia with Maturation, CG17835, Acute, Znfpr1b1, Acute Nonlymphoblastic Leukemias, Acute Myeloblastic Leukemias, Acute Myelogenous Leukemias, inv, Prdm3, BLR2, DmelCG17835, EBV-induced G-protein coupled receptor 1"],"additional_accession":[]},"is_claimable":false,"name":"ena-DATASET-ERASMUSMC-HEMA-27-01-2014-00:15:01:730-100 - samples","description":"In total 30 Acute Myeloid Leukemias with an acquired inv(3)(q21q26) or t(3;3)(q21;q26) have been characterized by whole transcriptome sequencing (RNA-Seq). The 3q-aberration leads to overexpression of the proto-oncogene EVI1, but the mechanism of overexpression has thus far been elusive. The RNA-Seq was integral in determining the precise enhancer inducing the overexpression and led to other key discoveries.","dates":{"updated":"2017-07-26 15:39:25"},"accession":"EGAD00001000726","cross_references":{"TAXONOMY":["9606"],"EGA":["EGAC00001000162","EGAS00001000669"]}}