{"database":"EGA","file_versions":[],"scores":null,"additional":{"omics_type":["Genomics"],"dataset_type":["N/A"],"full_dataset_link":["https://ega-archive.org/datasets/EGAD00001004861"],"sample_count":["396"],"description":["EGA dataset EGAD00001004861"],"repository":["EGA"],"title":["Germline and somatic variants in myelodysplastic syndrome and therapy-related myeloid neoplasms"],"name_synonyms":["Vasp, VASP, 907, DmelCG15112, ENHANCER OF ATNSI ACTIVITY, XXD, Data Set, 907 细胞, NICR1852., XD, Dhekelia, MENA, NDPP1, Eastern Sovereign Base Area, l(2)02029, Enb, enb, 907 cell, ENA, Ena, DHEKELIA, Dhekelia Sovereign Base Area, CG15112, ENA/VASP"],"description_synonyms":["setulae, Multipotent Bone Marrow Stromal Cells, Mesenchymal Stem Cell, Materials, High Throughput DNA Sequencing, DNS, ion, Nucleotide Sequencing, (Deoxyribonucleotide)n, Myelodysplasia, Massively-Parallel, supply, Mesenchymal Stem Cells, Stem Cells, Progenitor Cell, Stromal Cells, Mesenchymal Stromal Cells, Adipose Tissue Derived Mesenchymal Stromal Cell, Gene, Wharton's Jelly Cells, High-Throughput DNA, Prognostic Factors, Multipotent Mesenchymal Stromal Cell, Illumina, Deoxyribonucleic acids, Next-Generation Sequencing, bone marrow stromal cells, Hair, Mutations, stem cells, High-Throughput RNA Sequencing, Deoxyribonucleic Acid, Stromal Cell, Deep, Marrow, medulla ossea, Dysmyelopoietic Syndromes, Wharton Jelly Cells, Yellow, Massively Parallel Sequencing, mesenchymal precursor cell, Wharton's Jelly Cell, mesenchymal stromal cell, Lanugo, Deep Sequencing, Multipotent Mesenchymal Stromal Cells, Adipose Tissue-Derived Mesenchymal Stromal Cells, Adipose Derived Mesenchymal Stem Cells, thymus nucleic acid, Fetal Hairs, Ion Proton Sequencing, Prognoses, Fetal Hair, Hematopoetic Myelodysplasias, Genetic, Dysmyelopoietic Syndrome, Illumina Sequencing, distribution, coat/ hair, iones, vibrissa, mesenchymal progenitor cells, Double Stranded, mesenchymal, Bone Marrow Stromal Stem Cells, Deoxyribonucleic acid, Pyrosequencing, CFU-F, ions, MSC, Sequencing, Red Marrow, Bone Marrow Mesenchymal Stem Cells, High Throughput RNA Sequencing, Whartons Jelly Cells, quill, Fetal, Clients, therapy-related myeloid neoplasms, Syndrome, marrow stromal cells, Red, High-Throughput, RNA Sequencing, Double-Stranded DNA, (Deoxyribonucleotide)m, deoxyribonucleic acids, DNAn, Bone Marrow Mesenchymal Stem Cell, Adipose Derived Mesenchymal Stem Cell, myelodysplastic syndrome, High-Throughput RNA, fur, Myelodysplastic Syndrome, Adipose-Derived Mesenchymal Stem Cell, Data Set, DNAn+1, Progenitor Cells, High-Throughput DNA Sequencing, Mesenchymal Progenitor Cells, Hairs, Factor, Double-Stranded, Adipose Tissue-Derived Mesenchymal Stem Cell, Cistrons, Client, MDS, Hematopoetic, (Deoxyribonucleotide)n+m, Hematopoetic Myelodysplasia, Mesenchymal Stromal Cell, Ion Torrent Sequencing, medulla ossium, colony-forming unit-fibroblast, Stem Cell, Ionen, DNA Sequencing, Massively-Parallel Sequencing, Next-Generation, Genetic Materials, Ion Torrent, supply and distribution, ds-DNA, desoxyribose nucleic acid, Genetic Material, Next Generation Sequencing, Yellow Marrow, Bone Marrow Stromal Cell, Adipose-Derived, BMSC, whisker, Adipose-Derived Mesenchymal Stem Cells, mesenchymal stromal cells, Factors, Adipose Tissue Derived Mesenchymal Stromal Cells, medullary bone, medulla of bone, Prognostic, susceptibility to, Multipotent Bone Marrow Stromal Cell, hair, Adipose Tissue-Derived Mesenchymal Stromal Cell, Adipose Tissue Derived Mesenchymal Stem Cells, Prognostic Factor., Myelodysplastic, microchaeta, Adipose-Derived Mesenchymal Stromal Cells, Adipose Derived, High Throughput Sequencing, mesenchymal stem cell, Adipose Tissue-Derived Mesenchymal Stem Cells, Syndromes, Patient, Mesenchymal Progenitor Cell, Ion, High-Throughput Sequencing, Myelodysplasias, Material, Multipotent, ds DNA, Mesenchymal, Adipose Derived Mesenchymal Stromal Cells, Desoxyribonukleinsaeure, microarray, High Throughput Nucleotide Sequencing, Adipose Tissue Derived Mesenchymal Stem Cell, Cistron, TMN, DNA, Bone Marrow Stromal Cells, coat hair, Ion Proton, Bone, High-Throughput Nucleotide, Dysmyelopoietic"],"additional_accession":[]},"is_claimable":false,"name":"ena-DATASET-sacgf-23-03-2019-00:43:26:907-1 - samples","description":"Somatic mutation frequencies in patients with therapy-related myeloid neoplasms (129 patients, 181 samples including bone marrow, mesenchymal stromal cells and hair DNA) and primary myelodysplastic syndrome (108 patients, 215 samples including bone marrow, mesenchymal stromal cells and hair DNA) is assessed by deep sequencing of selected genes, using a Fluidigm Access Array, a Nimblegen capture panel and an Ion AmpliSeq panel. The dataset consists of paired fastq files obtained by either Hiseq (2x101bp) or Nextseq (2x150bp) Illumina sequencing. The mutational burden is found to be similar in both, however the distribution of variants is different. Correlation of the mutational spectrum with prognosis is also observed.","dates":{"updated":"2019-04-04 08:51:24"},"accession":"EGAD00001004861","cross_references":{"TAXONOMY":["9606"],"EGA":["EGAC00001000220","EGAS00001003547"]}}