<HashMap><database>EGA</database><scores/><additional><omics_type>Genomics</omics_type><dataset_type>N/A</dataset_type><full_dataset_link>https://ega-archive.org/datasets/EGAD00001006337</full_dataset_link><sample_count>278</sample_count><description>EGA dataset EGAD00001006337</description><repository>EGA</repository><title>Somatic mutations reveal embryonic genetic bottlenecks generating placental mosaicism</title></additional><is_claimable>false</is_claimable><name>EGAS00001003549-3-sc-2020-08-03T08:49:48Z - samples</name><description>The human placenta harbours chromosomal aberrations that are absent from the fetus in one to two percent of pregnancies. This confined mosaicism suggests that embryonic genetic bottlenecks exist, which phylogenetically segregate placental tissue. Here, we studied the somatic genetic landscape of human placentas by whole genome sequencing of 86 placental biopsies and of 106 microdissections.</description><dates><updated>2023-02-22 14:52:34</updated></dates><accession>EGAD00001006337</accession><cross_references><TAXONOMY>9606</TAXONOMY><EGA>EGAC00001000000</EGA><EGA>EGAS00001003457</EGA><EGA>EGAS00001003549</EGA><EGA>EGAS00001003297</EGA></cross_references></HashMap>