{"database":"EGA","file_versions":[],"scores":null,"additional":{"omics_type":["Genomics"],"dataset_type":["N/A"],"full_dataset_link":["https://ega-archive.org/datasets/EGAD00001011309"],"sample_count":["8"],"description":["EGA dataset EGAD00001011309"],"repository":["EGA"],"title":["Evaluating gene expression in aggressive B-cell lymphoma using a quantitative nuclease protection assay"],"additional_accession":[]},"is_claimable":false,"name":"DLBCLR_RNAseq - samples","description":"Diffuse large B-cell lymphoma (DLBCL) is the most common non-Hodgkin lymphoma (NHL), comprising 25-30% of all NHL in developed countries with an annual incidence in the USA of 7 cases/100000 persons/year. Collectively, DLBCL is classified based on a common morphological appearance of diffuse growth of large transformed B-cells, immunophenotype, high proliferation rate and aggressive behaviour. Despite these similarities, DLBCLs are a heterogeneous collection of malignancies with distinct clinical and molecular characteristics that do not always correlate with immunohistological features. This gene expression dataset includes transcriptomes of ABC-DLBCLs and of GCB-DLBCLs where cell of origin is determined by the HTG-EdgeSeq quantitative nuclease protection assay. Also included are clonality results from BCR profiling from high-grade B-cell lymphomas sequenced using a NOVA sequencer","dates":{"updated":"2023-09-06 15:51:15"},"accession":"EGAD00001011309","cross_references":{"TAXONOMY":["9606"],"EGA":["EGAC00001003392","EGAS00001007479"]}}