EGAGenomicsN/Ahttps://ega-archive.org/datasets/EGAD000010153911EGA dataset EGAD00001015391EGARNA-seq data of Metabolic profiling of patient-derived organoids reveals nucleotide synthesis as a metabolic vulnerability in malignant rhabdoid tumorsfalsePMCDS000ABR - samplesPatient-matched normal kidney organoid (103H) and MRT tumoroid (103T2) models were treated for 24h with either DMSO (ctrl), 400nM MTX, or 50nM BAY to investigate the direct effects of drug treatment on the expression of key metabolic enzymes in the nucleotide biosynthesis pathways.2024-08-08 14:49:08EGAD000010153919606EGAC00001001864EGAS00001007877