EGAGenomicsIllumina Genome Analyzer IIOtherhttps://ega-archive.org/studies/EGAS00001000069EGAEGA study EGAS00001000069Determination of the molecular nature of the Vel blood group by exome sequencingEGArestrictedWES, Complete Transcriptome, Complete, Complete Transcriptome Sequencing, Exome Sequencings, grupo, Complete Exome Sequencings, whole blood, ensemble, Complete Exome Sequencing, Whole Transcriptome Sequencing, Exome, Rest, Sequencing, group, set, Exome Sequencing, Whole Exome, grupos, Whole, Whole Exome Sequencing, Whole Transcriptome, Transcriptome Sequencing, Transcriptome Sequencings, groupe, Vel, Complete Exome., GruppeTransplant Donor, grupo, DNS, whole blood, (Deoxyribonucleotide)n, Acute onset., DNAn+1, Blood, Transplant, familial, Semen Donors, Double-Stranded, Deoxyribonucleic acids, group, (Deoxyribonucleotide)n+m, Readability, Deoxyribonucleic Acid, Donors, Donor, ds-DNA, desoxyribose nucleic acid, Blood Donor, thymus nucleic acid, ensemble, Organ Donor, Tissue, Rest, Double Stranded, Deoxyribonucleic acid, Understanding, Semen Donor, Transplant Donors, genetic, set, Semen, grupos, ds DNA, Desoxyribonukleinsaeure, inherited genetic, Double-Stranded DNA, Tissue Donor, (Deoxyribonucleotide)m, DNA, deoxyribonucleic acids, Ovum Donor, DNAn, constitutitional genetic, hereditary, Ovum, Ovum Donors, Organ Donors, groupe, Vel, Severe, Gruppe, OrganfalseDetermination of the molecular nature of the Vel blood group by exome sequencingThe genetic basis of the Vel group is yet to be determined. We have collected DNA samples from about 90 Vel negative blood donors by phenotyping 270,000 donors. Understanding the genetic basis of the Vel group could have clinical significance as transfusion of Vel positive blood to Vel negative recipients with anti-Vel can cause severe and acute haemolytic transfusion reactions.2017-08-24 20:50:42EGAS000010000699606EGAD00001000025EGAC00001000012