EGA00190GenomicsIllumina Genome Analyzer IICancer Genomicshttps://ega-archive.org/studies/EGAS00001000198EGAEGA study EGAS00001000198Myeloproliferative Disorder SequencingEGArestrictedMPD, malignant Growth, Individual Health, whole exome, malignancy, human being, Materials, DNS, wide/broad, not genetically inherited., MPN, (Deoxyribonucleotide)n, myeloproliferative tumor, malignant, DNAn+1, cell type cancer, chronic myeloproliferative disease, Gene, Normalcy, Double-Stranded, broad, Normalcies, Cistrons, Client, chronic, Deoxyribonucleic acids, gDNA, myeloproliferative neoplasms, (Deoxyribonucleotide)n+m, MT, Deoxyribonucleic Acid, malignant neoplasm (disease), organ system cancer, myeloproliferative disorder, Genetic Materials, NCI CTEP SDC Chronic Myeloproliferative Disease Sub-Category Terminology, Individual, ds-DNA, desoxyribose nucleic acid, neoplasm, Library, malignant tumour, Genetic Material, PCR, chronic myeloproliferative disorder, Normalities, CMPD, average, thymus nucleic acid, primary cancer, Genetic, Genomes, Normality, neoplasm (disease), Exomes, Double Stranded, U, Deoxyribonucleic acid, man, chronic myeloproliferative neoplasm, malignant tumor, human, CA, wide, Health, Patient, chronic myeloproliferative disorders, malignant neoplasm, malignant neoplastic disease, Material, Clients, ds DNA, Desoxyribonukleinsaeure, Cistron, Double-Stranded DNA, (Deoxyribonucleotide)m, DNA, deoxyribonucleic acids, DNAn, cancer, myeloproliferative neoplasmMPD, chronic myeloproliferative disorder, myeloproliferative neoplasms, CMPD, MPN, chronic myeloproliferative disorders, myeloproliferative neoplasm., myeloproliferative tumor, myeloproliferative disorder, chronic myeloproliferative disease, U, NCI CTEP SDC Chronic Myeloproliferative Disease Sub-Category Terminology, myeloproliferative neoplasm, chronic myeloproliferative neoplasm, chronic190.00.00.00.00.005860579888957434falseMyeloproliferative Disorder SequencingAgilent whole exome hybridisation capture will be performed on genomic DNA derived from 50 myeloproliferative disorder samples and matched normal DNA from the same patients. Three lanes of Illumina GA sequencing will be performed on the resulting 100 exome libraries and mapped to build 37 of the human reference genome to facilitate the identification of novel cancer genes. In addition, 500bp, NO_PCR total genomic libraries will be prepared from the same samples and five lanes of Illumina GA sequencing will be analysed to characterise genome wide, somatically acquired structural variation.2017-07-26 15:39:24EGAS000010001989606EGAD00001000102EGAC00001000010