{"database":"EGA","file_versions":[],"scores":null,"additional":{"omics_type":["Genomics"],"technology_type":["Illumina HiSeq 2000"],"study_type":["Cancer Genomics"],"full_dataset_link":["https://ega-archive.org/studies/EGAS00001000409"],"host":["EGA"],"description":["EGA study EGAS00001000409"],"dataset_title":["Chordoma Sequencing Project Whole Genome"],"repository":["EGA"],"category":["restricted"],"name_synonyms":["CHDM, whole genome., Chordomas, susceptibility to chordoma, chordoma, susceptibility to"],"description_synonyms":["Ribonucleic, Materials, DNS, RNA Sequence Determination, (Deoxyribonucleotide)n, HSN1E, Sequence Determination, Neoplasms, RNA Sequence, Benign Neoplasm, Gene, congenital defects, Tumor, Foundation, Malignant, chordoma, aplasia, Deoxyribonucleic acids, Mutations, Aim, AIM, Deoxyribonucleic Acid, Core Genome, Line, Gene Products, Analysis, defects, Non Polyadenylated, DNMT1, thymus nucleic acid, Complete, Whole Genome, Genetic, Malignancy, Genomes, DNMT1_HUMAN, Analyses, Determination, Accessory Genome, Complete Genome Sequencing, hypoplasia, Double Stranded, Deoxyribonucleic acid, Sequence Determinations, Sequencing, RNA Gene Products., Non-Polyadenylated RNA, Neoplasias, API6, RNA Sequence Analyses, malignant neoplasm, Whole, RNA Sequencing, Double-Stranded DNA, Malignancies, (Deoxyribonucleotide)m, deoxyribonucleic acids, DNAn, CXXC finger protein 9, Methylations, Cancer, Tumors, DNA MTase HsaI, Sequence Analyses, DNA (cytosine-5)-methyltransferase 1, RNA, Malignant Neoplasm, ribose nucleic acid, RNA Sequence Determinations, DNAn+1, DNMT, ribonucleic acids, Genome Sequencing, Cell Lines, RNS, Double-Stranded, MCMT, Cistrons, not genetically inherited, Pangenome, deformities, Cell, Determinations, (Deoxyribonucleotide)n+m, MT, Benign, Complete Genome, agenesis, yeast nucleic acid, DNA methyltransferase HsaI, Ribonukleinsaeure, Neoplasm, CHDM, sequence, core, Genetic Materials, pentosenucleic acids, Ribonucleic acids, methylation, ds-DNA, Chordomas, desoxyribose nucleic acid, Library, Genetic Material, Lines, CXXC9, atresia, ribonucleic acid, Acid, ADCADN, primary cancer, UNQ203/PRO229, CT-2, susceptibility to chordoma, DNA (cytosine-5-)-methyltransferase 1, Non Polyadenylated RNA, susceptibility to, malformations, Non-Polyadenylated, Benign Neoplasms, Cancers, whole genome, Ribonucleic Acid, malignant tumor, CXXC-type zinc finger protein 9, primary structure of sequence macromolecule, Malignant Neoplasms, Pan-genome, Material, birth defects, anomalies, RNA Sequence Analysis, ds DNA, Desoxyribonukleinsaeure, Cistron, DNA, Neoplasia, CLEC2C, m.HsaI"],"additional_accession":[]},"is_claimable":false,"name":"Chordoma Sequencing Project Whole Genome","description":"This is a continuation of the Chordoma Sequencing Project, prelim #G0175-122-CF. All cancers arise due to somatically acquired abnormalities in DNA sequence. Systematic sequencing of cancer genomes allows acquisition of complete catalogues of all classes of somatic mutation present in cancer. These mutation catalogues will allow identification of the somatically mutated cancer genes that are operative and characterise patterns of somatic mutation that may reflect previous exogenous and endogenous mutagenic exposures. In this application, we aim to perform whole genome sequencing on 10 chordoma matched genome pairs. The Chordoma Foundation will fund the RNA Sequencing/Methylation and SNP6 costs for this project while the whole genome and library sequencing will be covered under the CGP, 2012-2013 core WTSI internal funding. An additional sequencing of three cancer cell lines will be added to this work, financed by the Chordoma Foundation. In this project, the Chordoma foundation will pay for the additional costs of methylation, RNA Seq,","dates":{"updated":"2017-07-26 15:39:25"},"accession":"EGAS00001000409","cross_references":{"TAXONOMY":["9606"],"EGA":["EGAD00001000721","EGAC00001000010"]}}