{"database":"EGA","file_versions":[],"scores":null,"additional":{"omics_type":["Genomics"],"technology_type":["Illumina HiSeq 2000, ILLUMINA, Illumina HiSeq 2500"],"study_type":["Cancer Genomics"],"full_dataset_link":["https://ega-archive.org/studies/EGAS00001000570"],"host":["EGA"],"description":["EGA study EGAS00001000570"],"dataset_title":["Targeted sequencing of genes recurrently mutated in AML - part2","Natural history of clonal haematopoiesis (2017-09-04)"],"category":["restricted"],"repository":["EGA"],"name_synonyms":["Runx-1, aml, leukemia, Acute myelogenous leukemia, Leukemia, Materials, Genetic, acute non lymphoblastic leukemia, Myeloid, Myeloblastic, Xaml1, Acute Myeloblastic Leukemia, susceptibility to, Acute Myeloid Leukemia, Gene, aml1., amlcr1, Cistrons, pebp2ab, AML, XAML, Acute, acute non lymphoblastic leukaemia, Material, aml-1, Genetic Materials, Cistron, ANLL, acute myeloid, aml1-evi-1, cbfa2, evi-1, Genetic Material, acute myelogenous"],"description_synonyms":["Myelocytic, acute myeloblastic leukemia, Materials, human being, acute myelogenous leukemia, Malignant Neoplasm, Complete Exome Sequencings, acute myeloblastic leukaemia, acute myelogenous leukaemia, Neoplasms, Modern, Exome, Benign Neoplasm, Gene, Tumor, Cistrons, Malignant, gDNA, Human, Mutations, method, Exome Sequencing, MT, Benign, Homo sapiens, method used in an experiment, Neoplasm, Genetic Materials, Whole Transcriptome, Transcriptome Sequencing, Library, Man, Genetic Material, acute, WES, Complete Transcriptome, primary cancer, Leukemia, Complete, Complete Transcriptome Sequencing, Exome Sequencings, Genetic, Man (Taxonomy), Genomes, Malignancy, Complete Exome Sequencing, Whole Transcriptome Sequencing, acute myeloid leukemia, Benign Neoplasms, acute myeloid leukaemia, INSDC_feature:gene, whole genome, Cancers, study protocol, malignant tumor, human, Sequencing, Malignant Neoplasms, plan specification, Neoplasias, Whole Exome, Material, malignant neoplasm, Modern Man, Whole, Whole Exome Sequencing, Cistron, Malignancies, Transcriptome Sequencings, AML - acute Myeloid Leukemia, Neoplasia, Complete Exome., Cancer, Tumors"],"additional_accession":[]},"is_claimable":false,"name":"Targeted sequencing of genes recurrently mutated in AML   part2","description":"Genomic libraries will be generated from total genomic DNA derived from 4000 samples with Acute Myeloid Leukaemia. Libraries will be enriched for a selected panel of genes using a bespoke pulldown protocol. 64 Samples will be individually barcoded and subjected to up to one lanes of Illumina HiSeq. Paired reads will be mapped to build 37 of the human reference genome to facilitate the characterisation of known gene mutations in cancer as well as the validation of potentially novel variants identified by prior exome sequencing.","dates":{"updated":"2020-07-16 15:33:08"},"accession":"EGAS00001000570","cross_references":{"TAXONOMY":["9606"],"EGA":["EGAD00001003703","EGAD00001000747","EGAC00001000000"]}}