EGAGenomicsHiSeq X Ten, Illumina HiSeq 2000Whole Genome Sequencinghttps://ega-archive.org/studies/EGAS00001000733EGAEGA study EGAS00001000733Barcelona kids with melanomaEGArestrictedmelanoma (disease), malignant melanoma, Melanomas, Melanoma, Malignant Melanomas, melanoma, Naevocarcinoma., Malignant, malignant, Malignant Melanomaother disease, IPP2A2, Materials, degree (angle), Neoplasms, Benign Neoplasm, Gene, Tumor, composed of, Malignant, PHAPII, Symptoms and Signs, CG11121, 5730420M11Rik, Mutations, melanoma (disease), old, melanoma, diseases, DmelCG11121, disease or disorder, diseases and disorders, Finding, SET, human disease, somda, Genetic, Malignancy, TAF-I, Naevocarcinoma, ipp2a2, 2pp2a, composition, SO, CG10574, DmelCG4299, genetic, non-neoplastic, Neoplasias, IGAAD, set, 2PP2A, DmelCG10574, taf-ibeta, malignant neoplasm, dSET, dSet, disorder, Homo sapiens disease, Malignancies, constitutitional genetic, So, Drl, Cancer, Tumors, Diagnostic Findings, phapii, SIGNS SYMPTOMS, Malignant Neoplasm, malignant, DESC, igaad, familial, disorders, StF-IT-1, Malignant Melanomas, medical condition, compositionality, Naevocarcinoma., Cistrons, group, Mdu, Melanomas, Signs and Symptoms, Melanoma, MT, Benign, I-2PP2A, mda, Malignant Melanoma, Dm I-2, I2PP2A, Diseases, Neoplasm, sequence, condition, Genetic Materials, ami, Genetic Material, primary cancer, HLA-DR-associated protein II, ensemble, DI-2, med, I-2Dm, content, Benign Neoplasms, CG4299, arc degree, Cancers, malignant tumor, primary structure of sequence macromolecule, Malignant Neoplasms, I-2PP1, dSET/TAF-Ibeta, disease, 2610030F17Rik, TAF-IBETA, Material, structure, malignant melanoma, Cistron, TAF-Ibeta, inherited genetic, AA407739, i2pp2a, hereditary, Clinical Finding, NeoplasiafalseBarcelona kids with melanomaThis set of samples is composed of eight young people (7-16 years old) that have developed melanoma with first-degree relatives that have also developed cancer, which suggests a genetic component to their disease. Here we want to sequence these samples in order to find the causative mutations. As these samples do not carry any of the high-penetrance mutations known to date, finding the genes(s) responsible will offer new insights into the genetic mechanisms underlying predisposition to melanoma.2017-07-26 15:39:27EGAS000010007339606EGAD00001002198EGAC00001000205