EGAGenomicsOtherhttps://ega-archive.org/studies/EGAS00001001044EGAEGA study EGAS00001001044Title not providedMutational landscape and clonal architecture in grade-II/III gliomasrestrictedEGAcg11478, Materials, Complete Exome Sequencings, Complete Exome, Effects, Exome, Longterm Effect, Gene, grade 2, CG30327, Cistrons, Long Term, Mutations, CG11478, Exome Sequencing, sampling, microarray., intermediate grade, CG6393, Long Term Effects, Genetic Materials, moderately differentiated, Whole Transcriptome, Transcriptome Sequencing, Effect, Genetic Material, Dmel_CG6393, DmelCG42257, WES, Complete Transcriptome, Complete, Complete Transcriptome Sequencing, Exome Sequencings, Genetic, G2, Longterm, Complete Exome Sequencing, Whole Transcriptome Sequencing, INSDC_feature:gene, Long-Term, grade II, Sequencing, Longterm Effects, Whole Exome, sample collection, Material, 65K, Whole, Whole Exome Sequencing, CG42257, Dmel_CG30327, Cistron, Long-Term Effect, snp, Transcriptome Sequencings, Long-Term EffectsRelapse, cg11478, Materials, Complete Exome Sequencings, Malignant Neoplasm, determination, Complete Exome, Effects, Neoplasms, Exome, Benign Neoplasm, Longterm Effect, Gene, grade 2, CG30327, Tumor, Cistrons, Malignant, Long Term, temporal, Mutations, CG11478, Exome Sequencing, relapse, sampling, Benign, Recrudescence, intermediate grade, CG6393, Long Term Effects, chemical analysis, Neoplasm, Genetic Materials, moderately differentiated, Whole Transcriptome, Transcriptome Sequencing, Relapses, Effect, Genetic Material, Dmel_CG6393, DmelCG42257, WES, Complete Transcriptome, Complete, Complete Transcriptome Sequencing, Exome Sequencings, Genetic, Malignancy, G2, Longterm, Recrudescences, Complete Exome Sequencing, Whole Transcriptome Sequencing, Benign Neoplasms, INSDC_feature:gene, Cancers, Long-Term, Recurrences., grade II, Sequencing, Longterm Effects, Malignant Neoplasms, Neoplasias, Whole Exome, sample collection, Material, 65K, Whole, heterogeneity, Whole Exome Sequencing, CG42257, Dmel_CG30327, microarray, Cistron, Long-Term Effect, snp, Malignancies, assay, other neoplasm, Transcriptome Sequencings, Long-Term Effects, Neoplasia, incidence, Cancer, TumorsfalseTo reveal the spectrum of gene mutations in grade II/III gliomas, whole exome sequencing of 52 samples including 4 multi-regional and 10 multi-time points sampling cases and 291 SNP-array were performed.To reveal the spectrum of gene mutations in grade II/III gliomas, whole exome sequencing of 52 samples including 4 multi-regional and 10 multi-time points sampling cases and 291 SNP-array were performed. Our analysis revealed high degrees of temporal/spatial heterogeneity generated during tumor expansion and relapse.2019-04-12 07:51:50EGAS000010010449606EGAD00010000682EGAD00010000684EGAD00001001213EGAD00010000688EGAD00010000686EGAC00001000273