{"database":"EGA","file_versions":[],"scores":null,"additional":{"omics_type":["Genomics"],"study_type":["Cancer Genomics"],"full_dataset_link":["https://ega-archive.org/studies/EGAS00001001933"],"host":["EGA"],"description":["EGA study EGAS00001001933"],"dataset_title":["The evolving mutational landscape of normal human esophagus","Somatic mutant selection is altered by prior NOTCH1 mutation in ageing esophageal epithelium","Metabolic context regulates the competitive fitness of oncogenic PIK3CA mutant clones in the normal esophagus","Competitive selection of somatic mutant clones in normal human skin varies with body site","Targeted sequencing of Human esophageal epithelium microbiopsies"],"category":["restricted"],"repository":["EGA"],"additional_accession":[]},"is_claimable":false,"name":"Mutant clone mapping in normal oesohagus and skin","description":"We will use targeted exome sequencing to examine normal appearing oesophageal epithelium and skin to determine the mutational burden.  DNA will be extracted from epithelia of a defined size and we will overlay positional information from the epithelial pieces to give clone maps over a wide area.  This will be done in both oesophageal epithelium and skin","dates":{"updated":"2024-10-16 12:35:42"},"accession":"EGAS00001001933","cross_references":{"TAXONOMY":["9606"],"EGA":["EGAD00001006194","EGAD00001006969","EGAD00001008281","EGAD00001015261","EGAD00001004158","EGAD00001015256","EGAC00001000000"]}}