EGAGenomicsILLUMINA, Illumina HiSeq 2000Otherhttps://ega-archive.org/studies/EGAS00001002352EGAEGA study EGAS00001002352There are 80 Brain cancer cases in this study and belong to GBM-CN project.EGArestrictedBrain, Brain Tumors, Biological Markers, Viral Marker, Primary Malignant Brain Neoplasms, Surrogate Endpoints, Clinical Markers, Laboratory, Clinical Marker, Neoplasms, Primary Brain Neoplasms, Cancer of Brain, Brain Neoplasms, Benign Neoplasm, Biochemical, Mini Exon, Endpoint, Tumor, Serum, Malignant, Brain Metastases, Surrogate End Points, Mutations, Surrogate Markers, Laboratory Markers, "brain neoplasm" EXACT [CSP2005:2006-2736], Recurrent Brain Tumors, Recurrent, Biological, Mini-Exon, malignant primary brain tumour, adult, average, treatment, study, Biomarker, Clinical, adult brain tumour, Malignancy, Biological Marker, Tissue, Brain Malignant Neoplasms, Primary Brain Tumors, Brain Tumor, "neoplasm of unspecified nature of brain (disorder)" EXACT [SNOMEDCT_2005_07_31:189537005]., genetic, Neoplasias, Immunologic Markers, Immune, Markers, neoplasm of brain, Brain Neoplasm, Primary Malignant Brain Tumors, Viral Markers, Recurrent Brain Tumor, disease management, Therapies, "neoplasm of brain (disorder)" EXACT [SNOMEDCT_2005_07_31:126952004], Malignancies, adult malignant brain neoplasm, constitutitional genetic, Immunologic Marker, malignant brain tumour, Biologic, Cancer, Tumors, Therapy, primary brain neoplasm, malignant tumour of adult brain, brain neoplasm, Intracranial Neoplasm, Viral, Malignant Brain Neoplasms, Malignant Neoplasm, Surrogate Endpoint, Brain Benign Neoplasm, Benign Brain Neoplasms, Serum Markers, primary malignant neoplasm of brain, familial, Malignant Primary Brain Neoplasms, WXS, End Point, malignant tumor of Brain, Biochemical Markers, Primary, Primary Brain Neoplasm, Biologic Marker, Primary Brain Tumor, Immune Marker, Benign, Brain Benign Neoplasms, "BT - Brain tumour" EXACT [SNOMEDCT_2005_07_31:254935002], Marker, Surrogate End Point, Brain Malignant Neoplasm, adult brain tumor, Neoplasm, Malignant Primary Brain Tumors, "tumor of the Brain" EXACT [NCI2004_11_17:C2907], Brain Cancers, Brain Metastase, malignant primary brain neoplasm, Malignant Brain Neoplasm, Biologic Markers, Intracranial Neoplasms, Primary Malignant, malignant primary brain tumor, Serum Marker, End Points, exonic region, Cancer of the Brain, Surrogate, Mini-Exons, Endpoints, Exon, Benign Neoplasms, tumor of the Brain, Cancers, Immunologic, primary brain tumor, Laboratory Marker, Brain Cancer, Treatments, Surrogate Marker, "neoplasm of unspecified nature of brain" EXACT [ICD9CM_2006:239.6], Malignant Neoplasms, Intracranial, Therapeutic, Biochemical Marker, BT - Brain tumour, Benign Brain Neoplasm, Treatment, malignant tumor of adult brain, inherited genetic, hereditary, Neoplasia, "neoplasm of unspecified nature of brain (disorder)" EXACT [SNOMEDCT_2005_07_31:189537005], Immune MarkersBrain, Brain Tumors, Biological Markers, Viral Marker, Primary Malignant Brain Neoplasms, Surrogate Endpoints, Clinical Markers, Laboratory, Clinical Marker, Neoplasms, Primary Brain Neoplasms, Cancer of Brain, Brain Neoplasms, Benign Neoplasm, Biochemical, Mini Exon, Endpoint, Tumor, Serum, Malignant, Brain Metastases, Surrogate End Points, Mutations, Surrogate Markers, Laboratory Markers, "brain neoplasm" EXACT [CSP2005:2006-2736], Recurrent Brain Tumors, Recurrent, Biological, Mini-Exon, malignant primary brain tumour, adult, average, treatment, study, Biomarker, Clinical, adult brain tumour, Malignancy, Biological Marker, Tissue, Brain Malignant Neoplasms, Primary Brain Tumors, Brain Tumor, "neoplasm of unspecified nature of brain (disorder)" EXACT [SNOMEDCT_2005_07_31:189537005]., genetic, Neoplasias, Immunologic Markers, Immune, Markers, neoplasm of brain, Brain Neoplasm, Primary Malignant Brain Tumors, Viral Markers, Recurrent Brain Tumor, disease management, Therapies, "neoplasm of brain (disorder)" EXACT [SNOMEDCT_2005_07_31:126952004], Malignancies, adult malignant brain neoplasm, constitutitional genetic, Immunologic Marker, malignant brain tumour, Biologic, Cancer, Tumors, Therapy, primary brain neoplasm, malignant tumour of adult brain, brain neoplasm, Intracranial Neoplasm, Viral, Malignant Brain Neoplasms, Malignant Neoplasm, Surrogate Endpoint, Brain Benign Neoplasm, Benign Brain Neoplasms, Serum Markers, primary malignant neoplasm of brain, familial, Malignant Primary Brain Neoplasms, WXS, End Point, malignant tumor of Brain, Biochemical Markers, Primary, Primary Brain Neoplasm, Biologic Marker, Primary Brain Tumor, Immune Marker, Benign, Brain Benign Neoplasms, "BT - Brain tumour" EXACT [SNOMEDCT_2005_07_31:254935002], Marker, Surrogate End Point, Brain Malignant Neoplasm, adult brain tumor, Neoplasm, Malignant Primary Brain Tumors, "tumor of the Brain" EXACT [NCI2004_11_17:C2907], Brain Cancers, Brain Metastase, malignant primary brain neoplasm, Malignant Brain Neoplasm, Biologic Markers, Intracranial Neoplasms, Primary Malignant, malignant primary brain tumor, Serum Marker, End Points, exonic region, Cancer of the Brain, Surrogate, Mini-Exons, Endpoints, Exon, Benign Neoplasms, tumor of the Brain, Cancers, Immunologic, primary brain tumor, Laboratory Marker, Brain Cancer, Treatments, Surrogate Marker, "neoplasm of unspecified nature of brain" EXACT [ICD9CM_2006:239.6], Malignant Neoplasms, Intracranial, Therapeutic, Biochemical Marker, BT - Brain tumour, Benign Brain Neoplasm, Treatment, malignant tumor of adult brain, inherited genetic, hereditary, Neoplasia, "neoplasm of unspecified nature of brain (disorder)" EXACT [SNOMEDCT_2005_07_31:189537005], Immune MarkersfalseIn this study, we performed exon sequencing (WXS) of 80 paired Brain cancer tumors and adjacent normal tissues to identify novel potential biomarkers. We extracted mutational signatures which induce somatic mutations . Our study covers a comprehensive genetic framework that can be used in clinical trials and treatment modalities in Brain cancer.In this study, we performed exon sequencing (WXS) of 80 paired Brain cancer tumors and adjacent normal tissues to identify novel potential biomarkers. We extracted mutational signatures which induce somatic mutations . Our study covers a comprehensive genetic framework that can be used in clinical trials and treatment modalities in Brain cancer.2020-07-16 15:33:08EGAS000010023529606EGAD00001003218EGAC00001000010